Technology Process of 4-Pentyn-2-ol, 5-phenyl-, (2S)-
There total 5 articles about 4-Pentyn-2-ol, 5-phenyl-, (2S)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
phenylacetylene;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 1h;
With
boron trifluoride diethyl etherate;
In
tetrahydrofuran;
at -78 ℃;
for 0.25h;
(S)-Propylene oxide;
In
tetrahydrofuran;
at -78 ℃;
for 3h;
Further stages.;
DOI:10.1021/ol0625280
- Guidance literature:
-
Multi-step reaction with 2 steps
1: NaOCl solution (buffered to pH 11.3), 4-phenylpyridine N-oxide / (S,S)-(salen)Mn(III) complex / benzene / 5 h / Ambient temperature
2: LiAlH4
With
lithium aluminium tetrahydride; 4-Phenylpyridine 1-oxide; NaOCl solution (buffered to pH 11.3);
(S,S)-(salen)manganese;
In
benzene;
DOI:10.1016/0040-4039(91)80212-O
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Pd(PPh3)4
2: NaOCl solution (buffered to pH 11.3), 4-phenylpyridine N-oxide / (S,S)-(salen)Mn(III) complex / benzene / 5 h / Ambient temperature
3: LiAlH4
With
lithium aluminium tetrahydride; 4-Phenylpyridine 1-oxide; NaOCl solution (buffered to pH 11.3);
tetrakis(triphenylphosphine) palladium(0); (S,S)-(salen)manganese;
In
benzene;
DOI:10.1016/0040-4039(91)80212-O