Propanoic acid, 2,2-dimethyl-3-(phenylmethoxy)-, 5-cyano-4-[[2,2-dimethyl-1-oxo-3-(phenylmethoxy)propyl]amino]-2-fluoro -6-methyl[1,1'-biphenyl]-3-yl ester

Base Information

Chemical Name:Propanoic acid, 2,2-dimethyl-3-(phenylmethoxy)-, 5-cyano-4-[[2,2-dimethyl-1-oxo-3-(phenylmethoxy)propyl]amino]-2-fluoro -6-methyl[1,1'-biphenyl]-3-yl ester
CAS No.:927389-74-0
Molecular Formula:C₃₈H₃₉FN₂O₅
Molecular Weight:622.736
Hs Code.:

Propanoic acid, 2,2-dimethyl-3-(phenylmethoxy)-,
5-cyano-4-[[2,2-dimethyl-1-oxo-3-(phenylmethoxy)propyl]amino]-2-fluoro
-6-methyl[1,1'-biphenyl]-3-yl ester

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Chemical Property of Propanoic acid, 2,2-dimethyl-3-(phenylmethoxy)-, 5-cyano-4-[[2,2-dimethyl-1-oxo-3-(phenylmethoxy)propyl]amino]-2-fluoro -6-methyl[1,1'-biphenyl]-3-yl ester

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Technology Process of Propanoic acid, 2,2-dimethyl-3-(phenylmethoxy)-, 5-cyano-4-[[2,2-dimethyl-1-oxo-3-(phenylmethoxy)propyl]amino]-2-fluoro -6-methyl[1,1'-biphenyl]-3-yl ester

There total 1 articles about Propanoic acid, 2,2-dimethyl-3-(phenylmethoxy)-, 5-cyano-4-[[2,2-dimethyl-1-oxo-3-(phenylmethoxy)propyl]amino]-2-fluoro -6-methyl[1,1'-biphenyl]-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 927388-83-8
2-amino-4-fluoro-3-hydroxy-6-methyl-5-phenylbenzonitrile

: 927389-73-9
3-(benzyloxy)-N-(3-cyano-6-fluoro-5-hydroxy-2-methyl[1,1'-biphenyl]-4-yl)-2,2-dimethylpropanamide

: 927389-74-0
4-{[3-(benzyloxy)-2,2-dimethylpropanoyl]amino}-5-cyano-2-fluoro-6-methyl[1,1'-biphenyl]-3-yl 3-(benzyloxy)-2,2-dimethylpropanoate

Guidance literature:: 3-(benzyloxy)-2,2-dimethylpropionic acid; In thionyl chloride; at 50 ℃; for 18h;

2-amino-4-fluoro-3-hydroxy-6-methyl-5-phenylbenzonitrile; With sodium hydrogencarbonate; In tetrahydrofuran; at 0 - 20 ℃; for 72h; Product distribution / selectivity;