3-(4-(Dimethylamino)phenyl)-2-(4-fluorophenyl)acrylonitrile

Base Information

Chemical Name:3-(4-(Dimethylamino)phenyl)-2-(4-fluorophenyl)acrylonitrile
CAS No.:397-91-1
Molecular Formula:C17H15FN2
Molecular Weight:266.3128
Hs Code.:
NSC Number:405095
Nikkaji Number:J3.360.967A
ChEMBL ID:CHEMBL2030540

Synonyms:3-(4-(Dimethylamino)phenyl)-2-(4-fluorophenyl)acrylonitrile;397-91-1;NSC405095;NSC 405095;(2Z)-3-[4-(dimethylamino)phenyl]-2-(4-fluorophenyl)prop-2-enenitrile;CHEMBL2030540;SCHEMBL14964722;(Z)-3-(4-dimethylaminophenyl)-2-(4-fluorophenyl)prop-2-enenitrile;STK201649;AKOS000337518;NSC-405095

Suppliers and Price of 3-(4-(Dimethylamino)phenyl)-2-(4-fluorophenyl)acrylonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 3-(4-(Dimethylamino)phenyl)-2-(4-fluorophenyl)acrylonitrile

Chemical Property:

Vapor Pressure:1.07E-06mmHg at 25°C
Boiling Point:402.8°Cat760mmHg
Flash Point:197.4°C
Density:1.167g/cm³
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:266.12192665
Heavy Atom Count:20
Complexity:377

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=CC=C(C=C1)C=C(C#N)C2=CC=C(C=C2)F
Isomeric SMILES:CN(C)C1=CC=C(C=C1)/C=C(\C#N)/C2=CC=C(C=C2)F

Technology Process of 3-(4-(Dimethylamino)phenyl)-2-(4-fluorophenyl)acrylonitrile

There total 3 articles about 3-(4-(Dimethylamino)phenyl)-2-(4-fluorophenyl)acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 459-22-3
4-fluorophenylacetonitrile

: 100-10-7
4-dimethylamino-benzaldehyde

: 397-91-1
(Z)-3-[4-(dimethylamino)phenyl]-2-(4-fluorophenyl)acrylonitrile

Guidance literature:: With pyrrolidine; In methanol;
DOI:10.1021/jm2017122

Reference yield:

: 352-32-9
p-fluorotoluene

: 397-91-1
4-Fluor-4'-dimethylamino-α-cyan-stilben

Guidance literature:: Multi-step reaction with 3 steps

1: Cl₂ / Irradiation

3: NaOEt / ethanol

With sodium ethanolate; chlorine; In ethanol;