Fomannoxin

Base Information

• Chemical Name: Fomannoxin
• CAS No.: 63587-64-4
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.226
• Hs Code.: 2932999099
• Mol file: 63587-64-4.mol

Synonyms:5-Benzofurancarboxaldehyde,2,3-dihydro-2-(1-methylethenyl)-, (S)-; (+)-Fomannoxin; FD 78a; Fomannoxin

Chemical Property of Fomannoxin

Chemical Property:

• Vapor Pressure: 0.000681mmHg at 25°C
• Boiling Point: 308.4°C at 760 mmHg
• Flash Point: 138.9°C
• PSA: 26.30000
• Density: 1.128g/cm³
• LogP: 2.37870

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Fomannoxin

There total 2 articles about Fomannoxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

(S)-2-(prop-1-en-2-yl)-2,3-dihydrobenzofuran (77341-30-1) + N-methyl-N-phenylformamide (93-61-8) → fomannoxin (63587-64-4)

Guidance literature:

With trichlorophosphate; at 90 ℃; for 1h;

DOI:10.1246/cl.1980.1581

Reference yield:

opt.-akt. 2-(2,3-Dihydro-2-benzofuryl)-2-propanol (77397-62-7) → fomannoxin (63587-64-4)

Guidance literature:

Multi-step reaction with 2 steps

1: phenylisocyanate / 20 h / Heating

2: 19 percent / POCl₃ / 1 h / 90 °C

With phenyl isocyanate; trichlorophosphate;

DOI:10.1246/cl.1980.1581

Reference yield:

fomannoxin (63587-64-4) → (+)-2-isopropenyl-2,3-dihydrobenzofuran-5-methanol (63587-65-5)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 2h;

upstream raw materials:

(S)-2-(prop-1-en-2-yl)-2,3-dihydrobenzofuran

N-methyl-N-phenylformamide

opt.-akt. 2-(2,3-Dihydro-2-benzofuryl)-2-propanol

Downstream raw materials:

(+)-2-isopropenyl-2,3-dihydrobenzofuran-5-methanol