Hexanoic acid, 5-methyl-3-[[[(1S)-1-[(methylamino)carbonyl]-3-phenylpropyl]amino]carb onyl]-, 1,1-dimethylethyl ester, (3S)-

Base Information

• Chemical Name: Hexanoic acid, 5-methyl-3-[[[(1S)-1-[(methylamino)carbonyl]-3-phenylpropyl]amino]carb onyl]-, 1,1-dimethylethyl ester, (3S)-
• CAS No.: 927828-17-9
• Molecular Formula: C23H36N2O4
• Molecular Weight: 404.55
• Mol file: 927828-17-9.mol

Synonyms:

Chemical Property of Hexanoic acid, 5-methyl-3-[[[(1S)-1-[(methylamino)carbonyl]-3-phenylpropyl]amino]carb onyl]-, 1,1-dimethylethyl ester, (3S)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Hexanoic acid, 5-methyl-3-[[[(1S)-1-[(methylamino)carbonyl]-3-phenylpropyl]amino]carb onyl]-, 1,1-dimethylethyl ester, (3S)-

There total 1 articles about Hexanoic acid, 5-methyl-3-[[[(1S)-1-[(methylamino)carbonyl]-3-phenylpropyl]amino]carb onyl]-, 1,1-dimethylethyl ester, (3S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

(S)-2-(2-(tert-butoxy)-2-oxoethyl)-4-methylpentanoic acid (157542-03-5) + (S)-2-amino-N-methyl-4-phenylbutanamide (245487-53-0) → (S)-tert-butyl 5-methyl-3-((S)-1-(methylamino)-1-oxo-4-phenylbutan-2-ylcarbamoyl)hexanoate (927828-17-9)

Guidance literature:

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield: 100.0%

(S)-tert-butyl 5-methyl-3-((S)-1-(methylamino)-1-oxo-4-phenylbutan-2-ylcarbamoyl)hexanoate (927828-17-9) → (S)-5-methyl-3-((S)-1-(methylamino)-1-oxo-4-phenylbutan-2-ylcarbamoyl)hexanoic acid (927828-13-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.75h;

upstream raw materials:

(S)-2-(2-(tert-butoxy)-2-oxoethyl)-4-methylpentanoic acid

(S)-2-amino-N-methyl-4-phenylbutanamide

Downstream raw materials:

(S)-5-methyl-3-((S)-1-(methylamino)-1-oxo-4-phenylbutan-2-ylcarbamoyl)hexanoic acid