Methanesulfonamide,N-[6-chloro-3-[(4,5-dihydro-1H-imidazol-2-yl)methoxy]-2-methylphenyl]-,hydrochloride (1:1)

Base Information

• Chemical Name: Methanesulfonamide,N-[6-chloro-3-[(4,5-dihydro-1H-imidazol-2-yl)methoxy]-2-methylphenyl]-,hydrochloride (1:1)
• CAS No.: 219311-43-0
• Molecular Formula: C₁₂H₁₆ClN₃O₃S*ClH
• Molecular Weight: 354.257
• Mol file: 219311-43-0.mol

Synonyms:Methanesulfonamide,N-[6-chloro-3-[(4,5-dihydro-1H-imidazol-2-yl)methoxy]-2-methylphenyl]-,monohydrochloride (9CI); Dabuzalgron hydrochloride; Ro 115-1240; Ro115-1240/190

Chemical Property of Methanesulfonamide,N-[6-chloro-3-[(4,5-dihydro-1H-imidazol-2-yl)methoxy]-2-methylphenyl]-,hydrochloride (1:1)

Chemical Property:

• Vapor Pressure: 5.88E-11mmHg at 25°C
• Boiling Point: 521.1°Cat760mmHg
• Flash Point: 268.9°C
• PSA: 88.17000
• Density: g/cm³
• LogP: 3.12060

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Treatment of stress urinary incontinence.

Technology Process of Methanesulfonamide,N-[6-chloro-3-[(4,5-dihydro-1H-imidazol-2-yl)methoxy]-2-methylphenyl]-,hydrochloride (1:1)

There total 2 articles about Methanesulfonamide,N-[6-chloro-3-[(4,5-dihydro-1H-imidazol-2-yl)methoxy]-2-methylphenyl]-,hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.6%

N-(6-chloro-3-cyanomethoxy-2-methyl phenyl)methanesulfonamide (219312-14-8) → N-[6-chloro-3-(4,5-dihydro-1H-imidazol-2-ylmethoxy)-2-methylphenyl]methanesulfonamide hydrochloride (219311-43-0)

Guidance literature:

With hydrogenchloride; In methanol; ethanol; dichloromethane; water; ethylenediamine; isopropyl alcohol;

Reference yield:

N-(6-chloro-3-cyanomethoxy-2-methyl phenyl)methanesulfonamide (219312-14-8) + 2-(3-aminophenoxy)acetonitrile (219312-01-3) → N-[6-chloro-3-(4,5-dihydro-1H-imidazol-2-ylmethoxy)-2-methylphenyl]methanesulfonamide hydrochloride (219311-43-0)

Guidance literature:

upstream raw materials:

N-(6-chloro-3-cyanomethoxy-2-methyl phenyl)methanesulfonamide

2-(3-aminophenoxy)acetonitrile