3-hydroxy-N-(2'-biphenyl)-2-naphthalenecarboxamide phosphate

Base Information

• Chemical Name: 3-hydroxy-N-(2'-biphenyl)-2-naphthalenecarboxamide phosphate
• CAS No.: 140446-67-9
• Molecular Formula: C₂₃H₁₈NO₅P
• Molecular Weight: 419.373
• Mol file: 140446-67-9.mol

Synonyms:HNPP; HNPP(fluorescent detector)

Chemical Property of 3-hydroxy-N-(2'-biphenyl)-2-naphthalenecarboxamide phosphate

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 109.16000
• Density: 1.424g/cm³
• LogP: 5.61460

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-hydroxy-N-(2'-biphenyl)-2-naphthalenecarboxamide phosphate

There total 3 articles about 3-hydroxy-N-(2'-biphenyl)-2-naphthalenecarboxamide phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-hydroxy-N-2'-biphenyl-2-naphthalenecarboxamide (144077-66-7) → Phosphoric acid mono-[3-(biphenyl-2-ylcarbamoyl)-naphthalen-2-yl] ester (140446-67-9)

Guidance literature:

With phosphorus pentachloride; In 1,4-dioxane; at 50 ℃; for 1h;

DOI:10.1021/ac00080a022

Reference yield:

2-phenylaniline (90-41-5) → Phosphoric acid mono-[3-(biphenyl-2-ylcarbamoyl)-naphthalen-2-yl] ester (140446-67-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) PCl₃ / 1) xylene, 80 deg C, 10 min; 2) xylene, reflux, 2 h

2: PCl₅ / dioxane / 1 h / 50 °C

With phosphorus pentachloride; phosphorus trichloride; In 1,4-dioxane;

DOI:10.1021/ac00080a022

Reference yield:

3-Hydroxy-2-naphthoic acid (92-70-6) → Phosphoric acid mono-[3-(biphenyl-2-ylcarbamoyl)-naphthalen-2-yl] ester (140446-67-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.) PCl₃ / 1) xylene, 80 deg C, 10 min; 2) xylene, reflux, 2 h

2: PCl₅ / dioxane / 1 h / 50 °C

With phosphorus pentachloride; phosphorus trichloride; In 1,4-dioxane;

DOI:10.1021/ac00080a022

upstream raw materials:

3-hydroxy-N-2'-biphenyl-2-naphthalenecarboxamide

2-phenylaniline

3-Hydroxy-2-naphthoic acid

Refernces