Chemical Property of Valganciclovir
Chemical Property:
- Vapor Pressure:1.08E-16mmHg at 25°C
- Refractive Index:1.677
- Boiling Point:629.1 °C at 760 mmHg
- PKA:9.32±0.20(Predicted)
- Flash Point:334.3 °C
- PSA：171.37000
- Density:1.59 g/cm3
- LogP:-0.15520
- Purity/Quality:
-
98%, *data from raw suppliers
Valganciclovir 98%purewithdatedHPLCUVchromatogram *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
-
Uses
Antiviral. Valganciclovir-d8, is the labeled analogue of Valganciclovir (V092000), a pro-drug of Ganciclovir, used in treatment of retro-virus.
-
Indications
Valganciclovir (Valcyte) is
the L-valyl ester prodrug of ganciclovir.
-
Clinical Use
Oral valganciclovir is comparable to intravenous
ganciclovir for the treatment and suppression of CMV
retinitis in AIDS patients.
-
Drug interactions
Potentially hazardous interactions with other drugs
Antibacterials: increased risk of convulsions with
imipenem-cilastatin.
Antivirals: possibly increased didanosine
concentration; profound myelosuppression with
zidovudine - avoid if possible.
Mycophenolate: possibly increased concentrations of
both mycophenolic acid and ganciclovir.
Increased risk of myelosuppression with other
myelosuppressive drugs.
