2-Propenoic acid, 3-[2-(2-propen-1-yloxy)phenyl]-, 2-acetyl-3,5-dimethoxyphenyl ester

Base Information

• Chemical Name: 2-Propenoic acid, 3-[2-(2-propen-1-yloxy)phenyl]-, 2-acetyl-3,5-dimethoxyphenyl ester
• CAS No.: 928214-88-4
• Molecular Formula: C22H22O6
• Molecular Weight: 382.413
• Mol file: 928214-88-4.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 3-[2-(2-propen-1-yloxy)phenyl]-, 2-acetyl-3,5-dimethoxyphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 3-[2-(2-propen-1-yloxy)phenyl]-, 2-acetyl-3,5-dimethoxyphenyl ester

There total 3 articles about 2-Propenoic acid, 3-[2-(2-propen-1-yloxy)phenyl]-, 2-acetyl-3,5-dimethoxyphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2-allyloxycinnamic acid (91963-08-5) + 2-hydroxy-4,6-dimethoxyacetophenone (90-24-4) → 2'-(2-allyloxycinnamoyloxy)-4',6'-dimethoxyacetophenone (928214-88-4)

Guidance literature:

With trichlorophosphate; In pyridine; at 20 ℃; for 24h;

DOI:10.1515/HC.2006.12.2.141

Reference yield:

allyl 2-allyloxycinnamate → 2'-(2-allyloxycinnamoyloxy)-4',6'-dimethoxyacetophenone (928214-88-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / sodium hydroxide / methanol / 3 h / 60 - 70 °C

2: 68 percent / phosphorous oxychloride / pyridine / 24 h / 20 °C

With sodium hydroxide; trichlorophosphate; In pyridine; methanol;

DOI:10.1515/HC.2006.12.2.141

Reference yield:

o-Coumaric acid (614-60-8) → 2'-(2-allyloxycinnamoyloxy)-4',6'-dimethoxyacetophenone (928214-88-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / potassium carbonate / acetone / 48 h / Heating

2: 81 percent / sodium hydroxide / methanol / 3 h / 60 - 70 °C

3: 68 percent / phosphorous oxychloride / pyridine / 24 h / 20 °C

With sodium hydroxide; potassium carbonate; trichlorophosphate; In pyridine; methanol; acetone;

DOI:10.1515/HC.2006.12.2.141

upstream raw materials:

2-allyloxycinnamic acid

2-hydroxy-4,6-dimethoxyacetophenone

o-Coumaric acid