Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2R,3R)-, compd. with (1R)-1-(3-aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile (1:1)

Base Information

• Chemical Name: Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2R,3R)-, compd. with (1R)-1-(3-aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile (1:1)
• CAS No.: 928652-54-4
• Molecular Formula: C₁₈H₁₇FN₂O*C₂₀H₁₈O₈
• Molecular Weight: 682.702
• Mol file: 928652-54-4.mol

Synonyms:

Chemical Property of Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2R,3R)-, compd. with (1R)-1-(3-aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile (1:1)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2R,3R)-, compd. with (1R)-1-(3-aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile (1:1)

There total 1 articles about Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2R,3R)-, compd. with (1R)-1-(3-aminopropyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran carbonitrile (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

didesmethylcitalopram (62498-69-5) + Di-p-toluoyl-L-tartaric acid (32634-66-5) → C18H17FN2O*C20H18O8 (928652-54-4) + C18H17FN2O*C20H18O8 (928652-45-3)

Guidance literature:

In acetonitrile; at 27 ℃; for 0.25h; Resolution of racemate;

DOI:10.1021/op800252w

upstream raw materials:

didesmethylcitalopram

Di-p-toluoyl-L-tartaric acid