2-(4-Chlorophenoxy)-2-phenylacetic acid

Base Information

Chemical Name:2-(4-Chlorophenoxy)-2-phenylacetic acid
CAS No.:119061-18-6
Molecular Formula:C₁₄H₁₁ClO₃
Molecular Weight:262.693
Hs Code.:
European Community (EC) Number:863-768-3
DSSTox Substance ID:DTXSID30922862
Nikkaji Number:J2.436.784C
Mol file:119061-18-6.mol

Synonyms:(R)-isomer of 2-(4-(4-chlorophenyl)oxy)-2-phenylacetic acid;(S)-isomer of 2-(4-(4-chlorophenyl)oxy)-2-phenylacetic acid;2-(4-(4-chlorophenyl)oxy)-2-phenylacetic acid;2-(4-p-chlorophenyloxy)-2-phenylethanoic acid;2-CPOPA

Suppliers and Price of 2-(4-Chlorophenoxy)-2-phenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Chlorophenoxy)-2-phenylaceticAcid
250mg
$ 265.00

AK Scientific
2-(4-Chlorophenoxy)-2-phenylaceticacid
500mg
$ 334.00

AK Scientific
2-(4-Chlorophenoxy)-2-phenylaceticacid
100mg
$ 189.00

Total 3 raw suppliers

Chemical Property of 2-(4-Chlorophenoxy)-2-phenylacetic acid

Chemical Property:

Vapor Pressure:5.17E-07mmHg at 25°C
Boiling Point:396.9°Cat760mmHg
Flash Point:193.8°C
PSA：46.53000
Density:1.326g/cm³
LogP:3.54470
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:262.0396719
Heavy Atom Count:18
Complexity:268

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Chlorophenoxy)-2-phenylaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(=O)O)OC2=CC=C(C=C2)Cl

Technology Process of 2-(4-Chlorophenoxy)-2-phenylacetic acid

There total 5 articles about 2-(4-Chlorophenoxy)-2-phenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4870-65-9,31302-84-8
2-bromophenylacetic acid

: 106-48-9,82344-39-6
4-chloro-phenol

: 119061-18-6
(4-chloro-phenoxy)-phenyl-acetic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 24h; Heating;
DOI:10.1021/jm00037a023

Reference yield:

: 64102-32-5
ethyl 2-(4-chlorophenoxy)-2-phenylacetate

: 119061-18-6
(4-chloro-phenoxy)-phenyl-acetic acid

Guidance literature:: With potassium hydroxide; In methanol; for 20h; Yield given; Ambient temperature;

Reference yield:

: 10606-73-2,99531-04-1,116836-53-4,4773-33-5
ethyl 2-chloro-2-phenylacetate

: 119061-18-6
(4-chloro-phenoxy)-phenyl-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) dimethylacetamide, 1-1.5 h, 40 deg C; 2.) dimethylacetamide, 5 h, 90 deg C

2: KOH / methanol / 20 h / Ambient temperature

With potassium hydroxide; sodium hydride; In methanol;