2,3-DIHYDRO-INDOLE-1,6-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 6-METHYL ESTER

Base Information

• Chemical Name: 2,3-DIHYDRO-INDOLE-1,6-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 6-METHYL ESTER
• CAS No.: 928771-49-7
• Molecular Formula: C₁₆H₂₁NO₅
• Molecular Weight: 307.346
• Hs Code.: 2933990090
• Mol file: 928771-49-7.mol

Synonyms:O1-tert-butyl O6-methyl indole-1,6-dicarboxylate;1-tert-butyl-6-methylindoline-1,6-dicarboxylate;4-methoxy-2,3-dihydro-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester;

Chemical Property of 2,3-DIHYDRO-INDOLE-1,6-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 6-METHYL ESTER

Chemical Property:

• PSA: 55.84000
• LogP: 2.83580

Purity/Quality:

97% ^*data from raw suppliers

1-tert-Butoxycarbonyl-4-methoxy-indoline-6-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-DIHYDRO-INDOLE-1,6-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 6-METHYL ESTER

There total 1 articles about 2,3-DIHYDRO-INDOLE-1,6-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 6-METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

4-methoxy-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester (928771-48-6) + tert-butyldicarbonate (34619-03-9) → 4-methoxy-2,3-dihydro-indole-1,6-dicarboxylic acid 1-tert-butyl ester 6-methyl ester (928771-49-7)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; for 16h; Heating / reflux;

upstream raw materials:

4-methoxy-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester

tert-butyldicarbonate