7-deazainosine

Base Information

• Chemical Name: 7-deazainosine
• CAS No.: 2862-16-0
• Molecular Formula: C11H13 N3 O5
• Molecular Weight: 267.27
• Mol file: 2862-16-0.mol

Synonyms:4H-Pyrrolo[2,3-d]pyrimidin-4-one,3,7-dihydro-7-b-D-ribofuranosyl-(7CI); 7-(b-D-Ribofuranosyl)pyrrolo[2,3-d]pyrimidin-4-one;7-Deazainosine; Antibiotic XK 101-2; NSC 99439

Chemical Property of 7-deazainosine

Chemical Property:

• Vapor Pressure: 1.78E-16mmHg at 25°C
• Melting Point: 242.5°C
• Refractive Index: 1.4930 (estimate)
• Boiling Point: 624.8°Cat760mmHg
• PKA: 12.45±0.20(Predicted)
• Flash Point: 331.7°C
• PSA: 120.60000
• Density: 1.9g/cm³
• LogP: -1.66390

Purity/Quality:

97% ^*data from raw suppliers

7-DEAZAINOSINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-deazainosine

There total 12 articles about 7-deazainosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

tubercidin (69-33-0) → 7-deazainosine (2862-16-0)

Guidance literature:

With acetic acid; sodium nitrite; at 60 ℃; for 12h;

DOI:10.1080/15257770802089009

Reference yield: 84.0%

7-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidin-4(3H)-on (76567-72-1) → 7-deazainosine (2862-16-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 24h;

DOI:10.1002/cber.19801131031

Reference yield: 71.0%

4-methoxy-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine (16754-81-7) → 4-Hydroxy-7-β-D-ribofuranosyl-7H-pyrrolo<2,3-d>pyrimidin (2862-16-0)

Guidance literature:

With chloro-trimethyl-silane; sodium iodide; In acetonitrile; for 4h; Heating;

DOI:10.1021/jm060275a

upstream raw materials:

4-methoxy-7-(β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidine

7-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)pyrrolo<2,3-d>pyrimidin-4(3H)-on

4-methoxy-5-iodo-N7-(β-D–ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

4-chloro-5-iodo-7-[(2,3,5-tri-O-benzoyl)-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine