Technology Process of Undecanoic acid, 2,3-dihydroxy-10-methyl-6-(phenylmethoxy)-, ethyl
ester, (2R,3S,6R)-
There total 8 articles about Undecanoic acid, 2,3-dihydroxy-10-methyl-6-(phenylmethoxy)-, ethyl
ester, (2R,3S,6R)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
osmium(VIII) oxide; Hydroquinone 1,4-phthalazinediyl diether; methanesulfonamide;
potassium carbonate; potassium hexacyanoferrate(III);
In
water; toluene; tert-butyl alcohol;
at 0 ℃;
for 24h;
DOI:10.1002/ejoc.200600690
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: NaH / dimethylformamide / 0.5 h / 20 °C
1.2: 97 percent / tetra-n-butylammonium iodide / dimethylformamide / 1 h / 0 °C
2.1: BH3*DMS / tetrahydrofuran / 4 h / 0 - 20 °C
2.2: 88 percent / NaOH; H2O2 / methanol; H2O / 6 h / 20 °C
3.1: DMSO; oxalyl chloride / CH2Cl2 / 1.5 h / -78 - -60 °C
3.2: Et3N / CH2Cl2 / 1 h / -60 °C
4.1: 3.27 g / acetone / 24 h / 20 °C
5.1: 96 percent / osmium tetroxide; methanesulfonamide; (DHQ)2PHAL / K2CO3; K3Fe(CN)6 / toluene; 2-methyl-propan-2-ol; H2O / 24 h / 0 °C
With
osmium(VIII) oxide; Hydroquinone 1,4-phthalazinediyl diether; oxalyl dichloride; methanesulfonamide; dimethylsulfide borane complex; sodium hydride; dimethyl sulfoxide;
potassium carbonate; potassium hexacyanoferrate(III);
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene; tert-butyl alcohol;
4.1: Wittig reaction;
DOI:10.1002/ejoc.200600690
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 95 percent / CuI / tetrahydrofuran / 12 h / -78 °C
2.1: NaH / dimethylformamide / 0.5 h / 20 °C
2.2: 97 percent / tetra-n-butylammonium iodide / dimethylformamide / 1 h / 0 °C
3.1: BH3*DMS / tetrahydrofuran / 4 h / 0 - 20 °C
3.2: 88 percent / NaOH; H2O2 / methanol; H2O / 6 h / 20 °C
4.1: DMSO; oxalyl chloride / CH2Cl2 / 1.5 h / -78 - -60 °C
4.2: Et3N / CH2Cl2 / 1 h / -60 °C
5.1: 3.27 g / acetone / 24 h / 20 °C
6.1: 96 percent / osmium tetroxide; methanesulfonamide; (DHQ)2PHAL / K2CO3; K3Fe(CN)6 / toluene; 2-methyl-propan-2-ol; H2O / 24 h / 0 °C
With
copper(l) iodide; osmium(VIII) oxide; Hydroquinone 1,4-phthalazinediyl diether; oxalyl dichloride; methanesulfonamide; dimethylsulfide borane complex; sodium hydride; dimethyl sulfoxide;
potassium carbonate; potassium hexacyanoferrate(III);
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene; tert-butyl alcohol;
5.1: Wittig reaction;
DOI:10.1002/ejoc.200600690
