1-Piperazinepropanamide, N-(4-(((phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)-

Base Information

Chemical Name:1-Piperazinepropanamide, N-(4-(((phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)-
CAS No.:86523-77-5
Molecular Formula:C25H28N6O2
Molecular Weight:444.536
Hs Code.:
DSSTox Substance ID:DTXSID50235628
Wikidata:Q83117507
ChEMBL ID:CHEMBL55902
Mol file:86523-77-5.mol

Synonyms:BRN 5667972;86523-77-5;1-Piperazinepropanamide, N-(4-(((phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)-;N-(4-(((Phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)-1-piperazinepropanamide;CHEMBL55902;DTXSID50235628;LS-113215;1-Piperazinepropanamide,N-(4-(((phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)-

Suppliers and Price of 1-Piperazinepropanamide, N-(4-(((phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-PIPERAZINEPROPANAMIDE, N-(4-(((PHENYLAMINO)CARBONYL)AMINO)PHENYL)-4-(2-PYRIDINYL)- 95.00%
5MG
$ 504.71

Total 0 raw suppliers

Chemical Property of 1-Piperazinepropanamide, N-(4-(((phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)-

Chemical Property:

Vapor Pressure:2.06E-15mmHg at 25°C
Boiling Point:622.4°C at 760 mmHg
Flash Point:330.2°C
PSA：93.09000
Density:1.301g/cm³
LogP:4.03890
XLogP3:2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:444.22737416
Heavy Atom Count:33
Complexity:610

Purity/Quality:: 1-PIPERAZINEPROPANAMIDE, N-(4-(((PHENYLAMINO)CARBONYL)AMINO)PHENYL)-4-(2-PYRIDINYL)- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCC(=O)NC2=CC=C(C=C2)NC(=O)NC3=CC=CC=C3)C4=CC=CC=N4

Technology Process of 1-Piperazinepropanamide, N-(4-(((phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)-

There total 4 articles about 1-Piperazinepropanamide, N-(4-(((phenylamino)carbonyl)amino)phenyl)-4-(2-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 873-67-6
benzonitrile oxide

: 86523-76-4
N-(4-aminophenyl)-3-<4-(2-pyridinyl)-1-piperazinyl>propanamide

: 86523-77-5
N-[4-(3-Phenyl-ureido)-phenyl]-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide

Guidance literature:: In toluene; at 20 - 25 ℃; for 8h;
DOI:10.1021/jm00384a002

Reference yield:

: 34803-66-2
1-(2-pyridyl)piperazine

: 86523-77-5
N-[4-(3-Phenyl-ureido)-phenyl]-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 69 percent / benzene / Heating

2: 73 percent / H₂ / 10percent Pd/C / methanol / 3102.9 Torr

3: 73 percent / toluene / 8 h / 20 - 25 °C

With hydrogen; palladium on activated charcoal; In methanol; toluene; benzene;
DOI:10.1021/jm00384a002

Reference yield:

: 7766-38-3
N-(4-nitrophenyl) acrylamide

: 86523-77-5
N-[4-(3-Phenyl-ureido)-phenyl]-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: 69 percent / benzene / Heating

2: 73 percent / H₂ / 10percent Pd/C / methanol / 3102.9 Torr

3: 73 percent / toluene / 8 h / 20 - 25 °C

With hydrogen; palladium on activated charcoal; In methanol; toluene; benzene;
DOI:10.1021/jm00384a002