5-[(4-chlorophenyl)methylidene]-1,3-diazinane-2,4,6-trione

Base Information

• Chemical Name: 5-[(4-chlorophenyl)methylidene]-1,3-diazinane-2,4,6-trione
• CAS No.: 27402-31-9
• Molecular Formula: C11H7 Cl N2 O3
• Molecular Weight: 250.641
• Hs Code.: 2933540000
• Mol file: 27402-31-9.mol

Synonyms:Barbituricacid, 5-(p-chlorobenzylidene)- (8CI); NSC 636607

Chemical Property of 5-[(4-chlorophenyl)methylidene]-1,3-diazinane-2,4,6-trione

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 75.27000
• Density: 1.494g/cm³
• LogP: 1.74700

Purity/Quality:

99% ^*data from raw suppliers

5-(4-CHLORO-BENZYLIDENE)-PYRIMIDINE-2,4,6-TRIONE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-[(4-chlorophenyl)methylidene]-1,3-diazinane-2,4,6-trione

There total 2 articles about 5-[(4-chlorophenyl)methylidene]-1,3-diazinane-2,4,6-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

BARBITURIC ACID (67-52-7,944357-77-1) + 4-chlorobenzaldehyde (104-88-1) → 5-(4-chlorobenzylidene)barbituric acid (27402-31-9)

Guidance literature:

In ethanol; water monomer; for 0.5h; Reflux;

DOI:10.1016/j.molstruc.2012.09.021

Reference yield:

→ 5-(4-chlorobenzylidene)barbituric acid (27402-31-9)

Guidance literature:

Barbitursaeure, p-Chlorbenzaldehyd, Δ;

DOI:10.1007/BF00475868

Reference yield: 90.0%

1-aminoguanidine hydrochloride (1937-19-5,16139-18-7) + 5-(4-chlorobenzylidene)barbituric acid (27402-31-9) → 5-(4-chlorophenyl)-7-hydrazinopyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione (1001318-29-1)

Guidance literature:

With potassium carbonate; for 2h; Heating;

DOI:10.1002/jhet.5570440605

upstream raw materials:

BARBITURIC ACID

4-chlorobenzaldehyde

Downstream raw materials:

2'-(4-chlorophenyl)pyrimidine-5-spirocyclopropane-2,4,6(1H,3H,5H)-trione

5-<1-(4-chlorophenyl)-2-phenylethyl>barbituric acid

5-<1-(4-chlorophenyl)-2-(3-chlorophenyl)ethyl>barbituric acid

5-<1-(4-chlorophenyl)-2-phenylethyl>-2,4,6-trichloropyrimidine