Methyl bicyclo[4.1.0]heptane-1-carboxylate

Base Information

Chemical Name:Methyl bicyclo[4.1.0]heptane-1-carboxylate
CAS No.:92984-25-3
Molecular Formula:C9H14O2
Molecular Weight:154.20600
Hs Code.:
DSSTox Substance ID:DTXSID30540025

Synonyms:Methyl bicyclo[4.1.0]heptane-1-carboxylate;132903-60-7;Bicyclo[4.1.0]heptane-1-carboxylic acid, methyl ester, (-)- (9CI);92984-25-3;DTXSID30540025

Suppliers and Price of Methyl bicyclo[4.1.0]heptane-1-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl bicyclo[4.1.0]heptane-1-carboxylate

Chemical Property:

Boiling Point:190.4±8.0 °C(Predicted)
PSA：26.30000
Density:1.120±0.06 g/cm3(Predicted)
LogP:1.73970
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:154.099379685
Heavy Atom Count:11
Complexity:188

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C12CCCCC1C2

Technology Process of Methyl bicyclo[4.1.0]heptane-1-carboxylate

There total 7 articles about Methyl bicyclo[4.1.0]heptane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 118-90-1
ortho-methylbenzoic acid

: 92984-25-3,132903-60-7
methyl bicyclo<4.1.0>heptanecarboxylate

Guidance literature:: Multi-step reaction with 6 steps

1: 90.7 percent / conc.H₂SO₄ / 21 h / Heating

2: N-bromosuccinimide (NBS) / CCl₄ / 18 h / Heating

3: 92 percent / H₂ / 5percent Rh/C / methanol; acetic acid / 2.2 h / Ambient temperature

4: 70 percent / HCl (gas) / ethanol / 19 h / 0 °C

5: 0.8 g / NaH, ethyl glycolate / dimethylsulfoxide / 18 h / Ambient temperature

6: 0.35 g / diethyl ether / 5 °C

With hydrogenchloride; N-Bromosuccinimide; ethyl 2-hydroxyacetate; sulfuric acid; hydrogen; sodium hydride; Rh on carbon; In methanol; tetrachloromethane; diethyl ether; ethanol; acetic acid; dimethyl sulfoxide;
DOI:10.1021/jo00212a025

Reference yield:

: 87-41-2
2-benzofuran-1(3H)-one

: 92984-25-3,132903-60-7
methyl bicyclo<4.1.0>heptanecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / H₂ / 5percent Rh/C / methanol; acetic acid / 2.2 h / Ambient temperature

2: 70 percent / HCl (gas) / ethanol / 19 h / 0 °C

3: 0.8 g / NaH, ethyl glycolate / dimethylsulfoxide / 18 h / Ambient temperature

4: 0.35 g / diethyl ether / 5 °C

With hydrogenchloride; ethyl 2-hydroxyacetate; hydrogen; sodium hydride; Rh on carbon; In methanol; diethyl ether; ethanol; acetic acid; dimethyl sulfoxide;
DOI:10.1021/jo00212a025

Reference yield:

: 87-24-1
ethyl 2-methylbenzoate

: 92984-25-3,132903-60-7
methyl bicyclo<4.1.0>heptanecarboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: N-bromosuccinimide (NBS) / CCl₄ / 18 h / Heating

2: 92 percent / H₂ / 5percent Rh/C / methanol; acetic acid / 2.2 h / Ambient temperature

3: 70 percent / HCl (gas) / ethanol / 19 h / 0 °C

4: 0.8 g / NaH, ethyl glycolate / dimethylsulfoxide / 18 h / Ambient temperature

5: 0.35 g / diethyl ether / 5 °C

With hydrogenchloride; N-Bromosuccinimide; ethyl 2-hydroxyacetate; hydrogen; sodium hydride; Rh on carbon; In methanol; tetrachloromethane; diethyl ether; ethanol; acetic acid; dimethyl sulfoxide;
DOI:10.1021/jo00212a025