Normorphine-6-glucuronide

Base Information

Chemical Name:Normorphine-6-glucuronide
CAS No.:65060-95-9
Molecular Formula:C22H25 N O9
Molecular Weight:447.442
Hs Code.:
DSSTox Substance ID:DTXSID50983617
Nikkaji Number:J426.675G
Wikidata:Q82970538
Mol file:65060-95-9.mol

Synonyms:normorphine-6-glucuronide

Suppliers and Price of Normorphine-6-glucuronide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of Normorphine-6-glucuronide

Chemical Property:

Vapor Pressure:2.58E-23mmHg at 25°C
Boiling Point:745.1°C at 760 mmHg
Flash Point:404.4°C
PSA：157.94000
Density:1.68g/cm³
LogP:-0.89880
XLogP3:-2.6
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:3
Exact Mass:447.15293138
Heavy Atom Count:32
Complexity:808

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC2CC3=C4C15C2C=CC(C5OC4=C(C=C3)O)OC6C(C(C(C(O6)C(=O)O)O)O)O
Isomeric SMILES:C1CN[C@@H]2CC3=C4[C@@]15[C@H]2C=C[C@@H]([C@@H]5OC4=C(C=C3)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O
Uses Normorphine 6-O-β-D-Glucuronide is a metabolite of Morphine (M652290).

Technology Process of Normorphine-6-glucuronide

There total 5 articles about Normorphine-6-glucuronide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 466-97-7,13396-02-6,99295-16-6,142864-36-6
normorphine

: 65060-95-9
normorphin-6-yl-β-D-glucopyranosiduronate (NM-6-G)

Guidance literature:: Multi-step reaction with 5 steps

1: 790 mg / 5percent NaHCO₃

2: Ag₂CO₃ / benzene / 30 h / Heating

3: H₂ / Pd-C / methanol; CHCl₃

4: NaOMe

5: 0.43 N Ba(OH)2 / 2 h

With barium dihydroxide; hydrogen; sodium methylate; sodium hydrogencarbonate; silver carbonate; palladium on activated charcoal; In methanol; chloroform; benzene;
DOI:10.1248/cpb.37.955

Reference yield:

: 124667-85-2
N,O³-biscarbobenzoxynormorphine

: 65060-95-9
normorphin-6-yl-β-D-glucopyranosiduronate (NM-6-G)

Guidance literature:: Multi-step reaction with 4 steps

1: Ag₂CO₃ / benzene / 30 h / Heating

2: H₂ / Pd-C / methanol; CHCl₃

3: NaOMe

4: 0.43 N Ba(OH)2 / 2 h

With barium dihydroxide; hydrogen; sodium methylate; silver carbonate; palladium on activated charcoal; In methanol; chloroform; benzene;
DOI:10.1248/cpb.37.955

Reference yield:

: 124667-86-3
C₄₅H₄₅NO₁₆

: 65060-95-9
normorphin-6-yl-β-D-glucopyranosiduronate (NM-6-G)

Guidance literature:: Multi-step reaction with 3 steps

1: H₂ / Pd-C / methanol; CHCl₃

2: NaOMe

3: 0.43 N Ba(OH)2 / 2 h

With barium dihydroxide; hydrogen; sodium methylate; palladium on activated charcoal; In methanol; chloroform;
DOI:10.1248/cpb.37.955