Mefentanyl

Base Information

• Chemical Name: Mefentanyl
• CAS No.: 42045-86-3
• Molecular Formula: C23H30N2O
• Molecular Weight: 350.5
• DSSTox Substance ID: DTXSID30962228
• Nikkaji Number: J134.065D
• Wikipedia: 3-Methylfentanyl
• Wikidata: Q2030844
• Metabolomics Workbench ID: 61452
• ChEMBL ID: CHEMBL4748291
• Mol file: 42045-86-3.mol

Synonyms:3-methyl-fentanyl;3-methylfentanyl;3-methylfentanyl hydrochloride;3-methylfentanyl hydrochloride, cis-;3-methylfentanyl monohydrochloride;3-methylfentanyl monohydrochloride, (cis)-isomer;3-methylfentanyl mononitrate, (cis)-(+)-isomer;3-methylfentanyl oxalate (1:1), (cis)-(+-)-isomer;3-methylfentanyl oxalate (1:1), (cis)-(-)-isomer;3-methylfentanyl oxalate (1:1), (trans)-(+)-isomer;3-methylfentanyl oxalate (1:1), (trans)-(+-)-isomer;3-methylfentanyl, (3R,4S)-;3-methylfentanyl, (3S,4R)-;3-methylfentanyl, (cis)-(+)-isomer;3-methylfentanyl, (cis)-(-)-isomer;3-methylfentanyl, (cis)-isomer;3-methylfentanyl, (trans)-(+-)-isomer;3-methylfentanyl, cis-;Mefentanyl;N-(3-methyl-1-(2-phenylethyl)-4-piperidinyl)-N-phenylpropanamide

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Mefentanyl

Chemical Property:

• Vapor Pressure: 4.16E-09mmHg at 25°C
• Boiling Point: 472.8°C at 760 mmHg
• PKA: 9.17±0.20(Predicted)
• Flash Point: 184.5°C
• PSA: 23.55000
• Density: 1.064g/cm³
• LogP: 4.32060
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 350.235813585
• Heavy Atom Count: 26
• Complexity: 426

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)N(C1CCN(CC1C)CCC2=CC=CC=C2)C3=CC=CC=C3
• Uses: A potent analgesic drug. Controlled Substance

Technology Process of Mefentanyl

There total 2 articles about Mefentanyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ N-((3R,4R)-3-Methyl-1-phenethyl-piperidin-4-yl)-N-phenyl-propionamide (42045-86-3,53758-16-0,53758-18-2,53758-20-6,53758-22-8,65814-07-5,78995-17-2,78995-19-4)

Guidance literature:

Amin (10), Propionsaeureanhydrid;

DOI:10.1021/jm00256a003

Reference yield:

→ 3-methylfentanyl (42045-86-3)

Guidance literature:

Piperidin Vb, 1. Phenylacetaldehyd, 2. katalyt. Hydr. (Pd/C: 10percent);

DOI:10.1002/jps.2600620627