2-Amino-3-methylbutanamide hydrochloride

Base Information

• Chemical Name: 2-Amino-3-methylbutanamide hydrochloride
• CAS No.: 93169-29-0
• Molecular Formula: C5H12N2O.ClH
• Molecular Weight: 152.624
• Hs Code.: 2924199090
• Mol file: 93169-29-0.mol

Synonyms:DL-valine amide,hydrochloride;2-Amino-3-methylbutyramide hydrochloride;D-luciferin (firefly),monopotassium salt;D-Luciferenpotassiumsalt;BEETLE LUCIFERIN,POTASSIUM SALT;valine amide hydrochloride;D-LUCIFERIN,MONOPOTASSIUM SALT;D-LUCIFERIN FIREFLY,POTASSIUM SALT;4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4;potassiuM (S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylate;valinamide hydrochloride;D-LUCIFERIN SYNTHETIC POTASSIUM SALT;D-LUCIFERINPOTASSIUMSALT;D-Luciferin*K;DL-Valin-amid,Hydrochlorid;(S)-2-(6-hydroxy-benzothiazol-2-yl)-4,5-dihydro-thiazole-4-carboxylic acid,monopotassium salt;

Chemical Property of 2-Amino-3-methylbutanamide hydrochloride

Chemical Property:

• PSA: 69.11000
• LogP: 1.65760

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-3-methylbutanamideHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Amino-3-methylbutanamide hydrochloride

There total 1 articles about 2-Amino-3-methylbutanamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.7%

2-amino-3-methylbutyronitrile (4475-96-1) → 2-amino-3-methylbutanamide hydrochloride (93169-29-0)

Guidance literature:

With hydrogenchloride; 2-hydroxyethanethiol; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/S0040-4039(00)88755-9

Reference yield: 85.0%

di-tert-butyl dicarbonate (24424-99-5) + 2-amino-3-methylbutanamide hydrochloride (93169-29-0) → Boc-Val-NH2 (35150-08-4)

Guidance literature:

With triethylamine; In dichloromethane;

Reference yield: 75.0%

Glyoxal (131543-46-9,107-22-2) + 2-amino-3-methylbutanamide hydrochloride (93169-29-0) → 2-hydroxy-3-isopropyl-pyrazine (25680-59-5)

Guidance literature:

With sodium hydroxide; In methanol; water; at -35 - 20 ℃;

DOI:10.1002/jlcr.664

upstream raw materials:

2-amino-3-methylbutyronitrile

Downstream raw materials:

2-hydroxy-3-isopropyl-pyrazine

2-Isopropyl-3-methoxypyrazine

Boc-Val-NH₂

Refernces

• 1、 Lee,Goo,Lee,Lee. "Hydrolysis of various nitrile compounds to the amides by catalysis of 2-mercaptoethanol in a phosphate buffer". . p. 7439 - 7440. Retrieved 2007/10/02.