Meclizine Monohydrochloride

Base Information

• Chemical Name: Meclizine Monohydrochloride
• CAS No.: 31884-77-2
• Molecular Formula: C25H27ClN2.2ClH.H2O
• Molecular Weight: 481.87
• Hs Code.: 2933599550
• European Community (EC) Number: 252-932-4
• NSC Number: 757094,28728
• UNII: 008PUV3986
• DSSTox Substance ID: DTXSID80957624
• Wikidata: Q27231341
• NCI Thesaurus Code: C29245
• RXCUI: 82041
• ChEMBL ID: CHEMBL1085765
• Mol file: 31884-77-2.mol

Synonyms:Agyrax;Antivert;Bonamine;Bonine;Chiclida;D Vert;D-Vert;Dihydrochloride, Meclizine;DVert;Histametizyn;Hydrochloride, Meclizine;Meclizine;Meclizine Dihydrochloride;Meclizine Hydrochloride;Meclizine Monohydrochloride;Meclozine;Monohydrochloride, Meclizine;Parachloramine;Ru Vert M;Ru-Vert-M

Chemical Property of Meclizine Monohydrochloride

Chemical Property:

• Appearance/Colour: White solid
• Melting Point: 210-213 °C
• PSA: 15.71000
• LogP: 6.97110
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• Water Solubility.: Insoluble in water.
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 426.1629543
• Heavy Atom Count: 29
• Complexity: 448

Purity/Quality:

98% ^*data from raw suppliers

Meclizine dihydrochloride monohydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl
• Recent ClinicalTrials: Evaluation of Meclizine Orodispersible Tablet Pharmacokinetic in Human Volunteers
• Uses: Antiemetic and H1-histamine receptor antagonistMeclizine dihydrochloride monohydrate acts as an antiemetic. It is also used for the prevention and treatment of nausea during pregnancy. In addition to this, it is used in radiation sickness, vomiting or dizziness associated with motion sickness. Product purchased here is only for use in Research and Development. Antiemetic Meclizine Dihydrochloride Monohydrate is used for the prevention and treatment of nausea, vomiting, or dizziness associated with motion sickness.
• Therapeutic Function: Antinauseant