2-(4-nitrophenyl)-3H-imidazo[4,5-f]quinoline

Base Information

• Chemical Name: 2-(4-nitrophenyl)-3H-imidazo[4,5-f]quinoline
• CAS No.: 93201-84-4
• Molecular Formula: C₁₆H₁₀N₄O₂
• Molecular Weight: 290.281
• DSSTox Substance ID: DTXSID60538995
• Wikidata: Q82414589
• Mol file: 93201-84-4.mol

Synonyms:93201-84-4;2-(4-nitrophenyl)-3H-imidazo[4,5-f]quinoline;DTXSID60538995

Chemical Property of 2-(4-nitrophenyl)-3H-imidazo[4,5-f]quinoline

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 290.08037557
• Heavy Atom Count: 22
• Complexity: 419

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=CC3=C2N=C(N3)C4=CC=C(C=C4)[N+](=O)[O-])N=C1

Technology Process of 2-(4-nitrophenyl)-3H-imidazo[4,5-f]quinoline

There total 7 articles about 2-(4-nitrophenyl)-3H-imidazo[4,5-f]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

5,6-diaminoquinoline (42143-23-7) + 4-nitro-benzoic acid (62-23-7) → 2-(4-Nitrophenyl)-1H-imidazo<4,5-f>quinoline (93201-84-4)

Guidance literature:

at 200 - 220 ℃; for 4h;

Reference yield: 25.0%

4-nitrobenzaldehdye (555-16-8) + 5,6-diaminoquinoline (42143-23-7) → 2-(4-Nitrophenyl)-1H-imidazo<4,5-f>quinoline (93201-84-4) + 3-(4-Nitro-benzyl)-2-(4-nitro-phenyl)-3H-imidazo[4,5-f]quinoline (100672-29-5)

Guidance literature:

With acetic acid; for 3h; Ambient temperature;

Reference yield:

4-nitrobenzaldehdye (555-16-8) → 2-(4-Nitrophenyl)-1H-imidazo<4,5-f>quinoline (93201-84-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / methanol / 2 h / -5 °C

2: acetic acid / 3 h / Ambient temperature

With acetic acid; In methanol;

upstream raw materials:

4-nitrobenzaldehdye

5,6-diaminoquinoline

4-nitro-benzoic acid

N⁶-[1-(4-Nitro-phenyl)-meth-(E)-ylidene]-quinoline-5,6-diamine