7-[3-[4-(2,3-Dimethylphenyl)piperazinyl]propoxy]-2(1H)-quinolinone

Base Information

Chemical Name:7-[3-[4-(2,3-Dimethylphenyl)piperazinyl]propoxy]-2(1H)-quinolinone
CAS No.:111073-34-8
Molecular Formula:C24H29 N3 O2
Molecular Weight:391.506
Hs Code.:

Synonyms:OPC 4392

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-[3-[4-(2,3-Dimethylphenyl)piperazinyl]propoxy]-2(1H)-quinolinone

Chemical Property:

Vapor Pressure:8.38E-16mmHg at 25°C
Boiling Point:630.4°Cat760mmHg
Flash Point:335.1°C
PSA：48.83000
Density:1.15g/cm³
LogP:4.15120

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7-[3-[4-(2,3-Dimethylphenyl)piperazinyl]propoxy]-2(1H)-quinolinone

There total 3 articles about 7-[3-[4-(2,3-Dimethylphenyl)piperazinyl]propoxy]-2(1H)-quinolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 79145-59-8
7-(3-chloropropoxy)-2(1H)-quinolinone

: 1013-22-5
1-(2,3-dimethylphenyl)piperazine

: 111073-34-8
OPC 4392

Guidance literature:: With triethylamine; sodium iodide; In acetonitrile; 1.) 4 h, reflux; 2.) 4 h, reflux;
DOI:10.1248/cpb.36.4377

Reference yield:

: 70500-72-0
7-hydroxy-1H-quinolin-2-one

: 111073-34-8
OPC 4392

Guidance literature:: Multi-step reaction with 2 steps

1: 40 percent / KOH / propan-2-ol / 20 h / Heating

2: 76 percent / 1.) NaI; 2.) triethylamine / acetonitrile / 1.) 4 h, reflux; 2.) 4 h, reflux

With potassium hydroxide; triethylamine; sodium iodide; In isopropyl alcohol; acetonitrile;
DOI:10.1248/cpb.36.4377