1-[1-(3-Chlorophenyl)-2-dimethylaminoethyl]cyclohexanol

Base Information

Chemical Name:1-[1-(3-Chlorophenyl)-2-dimethylaminoethyl]cyclohexanol
CAS No.:93413-94-6
Molecular Formula:C₁₆H₂₄ClNO
Molecular Weight:281.826
Hs Code.:
DSSTox Substance ID:DTXSID70437627
Nikkaji Number:J347.747I
Pharos Ligand ID:VKQMGR881R2Z
ChEMBL ID:CHEMBL101899

Synonyms:CHEMBL101899;93413-94-6;SCHEMBL4736494;1-[1-(3-Chlorophenyl)-2-dimethylaminoethyl]cyclohexanol;DTXSID70437627;1-[1-(3-CHLOROPHENYL)-2-(DIMETHYLAMINO)ETHYL]CYCLOHEXAN-1-OL;BDBM50010858;PD091791;1-(1-(3-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol;1-[1-(3-Chloro-phenyl)-2-dimethylamino-ethyl]-cyclohexanol (HCl)

Suppliers and Price of 1-[1-(3-Chlorophenyl)-2-dimethylaminoethyl]cyclohexanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[1-(3-Chlorophenyl)-2-dimethylaminoethyl]cyclohexanol

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:281.1546421
Heavy Atom Count:19
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CC(C1=CC(=CC=C1)Cl)C2(CCCCC2)O

Technology Process of 1-[1-(3-Chlorophenyl)-2-dimethylaminoethyl]cyclohexanol

There total 4 articles about 1-[1-(3-Chlorophenyl)-2-dimethylaminoethyl]cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(3-Chloro-phenyl)-2-(1-hydroxy-cyclohexyl)-N,N-dimethyl-acetamide

: 93413-94-6
1-(1-(3-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol

Guidance literature:: With borane; In tetrahydrofuran;
DOI:10.1021/jm00172a035

Reference yield:

: 103752-77-8
2-(3-chlorophenyl)-N,N-dimethylacetamide

: 93413-94-6
1-(1-(3-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: lithium diisopropylamide / -78 °C

2: borane or AlH₃ / tetrahydrofuran

With borane; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1021/jm00172a035

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 93413-94-6
1-(1-(3-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol

Guidance literature:: Multi-step reaction with 2 steps

1: lithium diisopropylamide / -78 °C

2: borane or AlH₃ / tetrahydrofuran

With borane; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1021/jm00172a035