3,5,7-Trimethylimidazo[4,5-b]pyridin-2-amine

Base Information

Chemical Name:3,5,7-Trimethylimidazo[4,5-b]pyridin-2-amine
CAS No.:132898-06-7
Molecular Formula:C₉H₁₂N₄
Molecular Weight:176.221
Hs Code.:
DSSTox Substance ID:DTXSID30157839
Nikkaji Number:J848.049D
Wikidata:Q83026001
Mol file:132898-06-7.mol

Synonyms:3,5,7-trimethylimidazo[4,5-b]pyridin-2-amine;132898-06-7;3H-Imidazo(4,5-b)pyridin-2-amine, 3,5,7-trimethyl-;2-Amino-3,5,7-trimethylimidazo(4,5-b)pyridine;2-AMINO-3H-3,5,7-TRIMETHYLIMIDAZO(4,5-6)PYRIDINE;DTXSID30157839;LS-80170;3,5,7-Trimethyl-3H-imidazo[4,5-b]pyridin-2-amine;3H-Imidazo[4,5-b]pyridin-2-amine,3,5,7-trimethyl-

Suppliers and Price of 3,5,7-Trimethylimidazo[4,5-b]pyridin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE,3,5,7-TRIMETHYL- 95.00%
5MG
$ 497.96

Total 5 raw suppliers

Chemical Property of 3,5,7-Trimethylimidazo[4,5-b]pyridin-2-amine

Chemical Property:

Vapor Pressure:1.72E-05mmHg at 25°C
Boiling Point:364.1°Cat760mmHg
Flash Point:174°C
PSA：57.46000
Density:1.3g/cm³
LogP:1.09740
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:176.106196400
Heavy Atom Count:13
Complexity:196

Purity/Quality:

99% ^*data from raw suppliers

3H-IMIDAZO[4,5-B]PYRIDIN-2-AMINE,3,5,7-TRIMETHYL- 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC2=C1N=C(N2C)N)C

Technology Process of 3,5,7-Trimethylimidazo[4,5-b]pyridin-2-amine

There total 6 articles about 3,5,7-Trimethylimidazo[4,5-b]pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5407-87-4
2-Amino-4,6-dimethylpyridine

: 132898-06-7
3,5,7-Trimethyl-3H-imidazo[4,5-b]pyridin-2-ylamine

Guidance literature:: Multi-step reaction with 6 steps

1: 94 percent / Na₂CO₃ / acetone / Ambient temperature

2: 94 percent / lithium aluminum hydride / tetrahydrofuran / 1 h / Heating

3: 49 percent / Br₂, gl. AcOH / 1 h

4: 78 percent / H₂SO₄, KNO₃ / 3 h / 0 - 20 °C

5: H₂, aq. NH₃ / 10percent Pd/C / methanol / 50 °C / 2585.7 Torr

6: ethanol / 18 h / 120 °C

With ammonium hydroxide; lithium aluminium tetrahydride; sulfuric acid; hydrogen; bromine; sodium carbonate; acetic acid; potassium nitrate; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; acetone;
DOI:10.1002/jhet.5570340303

Reference yield:

: 99132-30-6
6-methylamino-2,4-dimethylpyridine

: 132898-06-7
3,5,7-Trimethyl-3H-imidazo[4,5-b]pyridin-2-ylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 49 percent / Br₂, gl. AcOH / 1 h

2: 78 percent / H₂SO₄, KNO₃ / 3 h / 0 - 20 °C

3: H₂, aq. NH₃ / 10percent Pd/C / methanol / 50 °C / 2585.7 Torr

4: ethanol / 18 h / 120 °C

With ammonium hydroxide; sulfuric acid; hydrogen; bromine; acetic acid; potassium nitrate; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1002/jhet.5570340303

Reference yield:

: 193690-53-8
5-bromo-4,6-dimethyl-2-methylaminopyridine

: 132898-06-7
3,5,7-Trimethyl-3H-imidazo[4,5-b]pyridin-2-ylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / H₂SO₄, KNO₃ / 3 h / 0 - 20 °C

2: H₂, aq. NH₃ / 10percent Pd/C / methanol / 50 °C / 2585.7 Torr

3: ethanol / 18 h / 120 °C

With ammonium hydroxide; sulfuric acid; hydrogen; potassium nitrate; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1002/jhet.5570340303