Ethyl 2,3-bis(2-chlorophenyl)-5-oxocyclopentanecarboxylate

Base Information

Chemical Name:Ethyl 2,3-bis(2-chlorophenyl)-5-oxocyclopentanecarboxylate
CAS No.:1830-05-3
Molecular Formula:C₂₀H₁₈Cl₂O₃
Molecular Weight:377.267
Hs Code.:
NSC Number:74713
DSSTox Substance ID:DTXSID40291298
Mol file:1830-05-3.mol

Synonyms:1830-05-3;ethyl 2,3-bis(2-chlorophenyl)-5-oxocyclopentanecarboxylate;NSC74713;NCIOpen2_009145;DTXSID40291298;NSC-74713

Suppliers and Price of Ethyl 2,3-bis(2-chlorophenyl)-5-oxocyclopentanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Ethyl 2,3-bis(2-chlorophenyl)-5-oxocyclopentanecarboxylate

Chemical Property:

Vapor Pressure:1.31E-08mmHg at 25°C
Boiling Point:459°C at 760 mmHg
Flash Point:161.8°C
Density:1.293g/cm³
XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:376.0632998
Heavy Atom Count:25
Complexity:495

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1C(C(CC1=O)C2=CC=CC=C2Cl)C3=CC=CC=C3Cl

Technology Process of Ethyl 2,3-bis(2-chlorophenyl)-5-oxocyclopentanecarboxylate

There total 1 articles about Ethyl 2,3-bis(2-chlorophenyl)-5-oxocyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1830-05-3
Ethyl (+/-)-4,5-bis(o-chlorophenyl)-2-oxocyclopentanecarboxylate

Guidance literature:: Aethyl-2-chlor-cinnamat, Na in sd. Ae.;

Reference yield:

: 1830-05-3
Ethyl (+/-)-4,5-bis(o-chlorophenyl)-2-oxocyclopentanecarboxylate

: 132490-32-5
(1S,2R,3S,5S)-2,3-Bis-(2-chloro-phenyl)-5-hydroxy-cyclopentanecarboxylic acid ethyl ester

: 132455-77-7
(1R,2S,3R,5S)-2,3-Bis-(2-chloro-phenyl)-5-hydroxy-cyclopentanecarboxylic acid ethyl ester

Guidance literature:: With (1+)*I(1-); hydrogen; at 60 ℃; for 74h; under 69873.2 Torr;
DOI:10.1016/S0040-4039(00)97275-7

Reference yield:

: 1830-05-3
Ethyl (+/-)-4,5-bis(o-chlorophenyl)-2-oxocyclopentanecarboxylate

: 373600-20-5
C₄₁H₃₆P₂

Guidance literature:: Multi-step reaction with 4 steps

1: H₂; ⁽¹⁺⁾*I^(1-) / 74 h / 60 °C / 66195.7 - 69873.2 Torr

2: HBr

3: HCl-Zn / diethyl ether

4: 1) Li (1percent Na) / 1) THF, -78 deg C to -60 deg C

With hydrogenchloride; lithium (1 percent sodium); (1+)*I(1-); hydrogen bromide; hydrogen; zinc; In diethyl ether;
DOI:10.1016/S0040-4039(00)97275-7