Unii-W6E59kdd9D

Base Information

Chemical Name:Unii-W6E59kdd9D
CAS No.:185679-16-7
Molecular Formula:C₂₄H₂₈N₂O₄
Molecular Weight:408.497
Hs Code.:
UNII:W6E59KDD9D
Nikkaji Number:J976.251E
Pharos Ligand ID:7S2BWLS69DGV
ChEMBL ID:CHEMBL321634

Synonyms:3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-propylaminopropionic acid;HQL 975;HQL-975

Suppliers and Price of Unii-W6E59kdd9D

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of Unii-W6E59kdd9D

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:408.20490738
Heavy Atom Count:30
Complexity:503

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCNC(CC1=CC=C(C=C1)OCCC2=C(OC(=N2)C3=CC=CC=C3)C)C(=O)O
Isomeric SMILES:CCCN[C@@H](CC1=CC=C(C=C1)OCCC2=C(OC(=N2)C3=CC=CC=C3)C)C(=O)O

Technology Process of Unii-W6E59kdd9D

There total 5 articles about Unii-W6E59kdd9D which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-3-{4-[2-(5-Methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-2-propylamino-propionic acid methyl ester

: 185679-16-7
3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)ethoxy]-phenyl}-2S-propylamino-propionic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; methanol;
DOI:10.1016/S0960-894X(01)00649-7

Reference yield:

: 4326-36-7
(S)-N-(tert-butoxycarbonyl)tyrosine methyl ester

: 185679-16-7
3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)ethoxy]-phenyl}-2S-propylamino-propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 79 percent / PPh₃; DIAD / toluene

2: 100 percent / 4M HCl / dioxane

3: NaBH(OAc)3 / CH₂Cl₂

4: aq. LiOH / tetrahydrofuran; methanol

With hydrogenchloride; lithium hydroxide; di-isopropyl azodicarboxylate; sodium tris(acetoxy)borohydride; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; toluene; 1: Mitsunobu reaction;
DOI:10.1016/S0960-894X(01)00649-7

Reference yield:

: 103788-65-4
(5-methyl-2-phenyloxazol-4-yl)ethanol

: 185679-16-7
3-{4-[2-(5-methyl-2-phenyl-oxazol-4-yl)ethoxy]-phenyl}-2S-propylamino-propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 79 percent / PPh₃; DIAD / toluene

2: 100 percent / 4M HCl / dioxane

3: NaBH(OAc)3 / CH₂Cl₂

4: aq. LiOH / tetrahydrofuran; methanol

With hydrogenchloride; lithium hydroxide; di-isopropyl azodicarboxylate; sodium tris(acetoxy)borohydride; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; toluene; 1: Mitsunobu reaction;
DOI:10.1016/S0960-894X(01)00649-7