{4-[bis(2-chloroethyl)amino]phenyl}methanol

Base Information

• Chemical Name: {4-[bis(2-chloroethyl)amino]phenyl}methanol
• CAS No.: 6563-15-1
• Molecular Formula: C11H15 Cl2 N O
• Molecular Weight: 248.1489

Synonyms:Benzylalcohol, p-[bis(2-chloroethyl)amino]- (7CI,8CI);4-[Bis(2-chloroethyl)amino]benzenemethanol; 4-[N-Bis(2-chloroethyl)amino]benzylalcohol; NSC 58605; p-Bis(2-chloroethyl)aminobenzyl alcohol

Chemical Property of {4-[bis(2-chloroethyl)amino]phenyl}methanol

Chemical Property:

• Vapor Pressure: 8.02E-07mmHg at 25°C
• Boiling Point: 391.2°Cat760mmHg
• Flash Point: 190.4°C
• Density: 1.259g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of {4-[bis(2-chloroethyl)amino]phenyl}methanol

There total 2 articles about {4-[bis(2-chloroethyl)amino]phenyl}methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(bis(2-chloroethyl)amino)benzaldehyde (1208-03-3) → (4-(bis(2-chloroethyl)amino)phenyl)methanol (6563-15-1)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1021/jm00337a010

Reference yield:

→ (4-(bis(2-chloroethyl)amino)phenyl)methanol (6563-15-1)

Guidance literature:

4--benzaldehyd in THF, wssr. NaBH4 / 20grad;

Reference yield:

(4-(bis(2-chloroethyl)amino)phenyl)methanol (6563-15-1) + C22H31ClN2O → C33H45Cl2N3O2

Guidance literature:

With potassium carbonate; In chloroform; for 20h; Reflux;

DOI:10.1016/j.bmcl.2015.08.035

upstream raw materials:

4-(bis(2-chloroethyl)amino)benzaldehyde

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