Pirmenol hydrochloride

Base Information

• Chemical Name: Pirmenol hydrochloride
• CAS No.: 61477-94-9
• Molecular Formula: C22H30N2O•ClH
• Molecular Weight: 375.00
• DSSTox Substance ID: DTXSID6021169
• NCI Thesaurus Code: C81547
• Mol file: 61477-94-9.mol

Synonyms:CI 845;cis-alpha-(3-(2,6-dimethyl-1-piperidinyl)propyl)-alpha-phenyl-2-pyridinemethanol monohydrochloride;pirmenol;pirmenol hydrochloride

Chemical Property of Pirmenol hydrochloride

Chemical Property:

• Vapor Pressure: 8.39E-11mmHg at 25°C
• Melting Point: 171-172 °C
• Boiling Point: 499.6°Cat760mmHg
• Flash Point: 256°C
• PSA: 36.36000
• Density: g/cm³
• LogP: 5.10050
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 374.2124913
• Heavy Atom Count: 26
• Complexity: 386

Purity/Quality:

99% ^*data from raw suppliers

Pirmenolhydrochloride >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCCC(N1CCCC(C2=CC=CC=C2)(C3=CC=CC=N3)O)C.Cl
• Isomeric SMILES: C[C@@H]1CCC[C@@H](N1CCCC(C2=CC=CC=C2)(C3=CC=CC=N3)O)C.Cl
• Description: Pirrnenol hydrochloride is a long-lasting Class la antiarrhythmic agent introduced in Japan in 1994. The spectrum of antiarrhythmic activity of pirmenol includes atrial and ventricular arrhythmias of diverse etiology. In clinical trials, pirmenol was found effective in the short- and mid-term treatment of chronic premature ventricular beats, with or without underlying heart disease. In patients with supraventricular tachycardia, a single oral dose of pirmenol was highly effective in suppressing induction of tachycardia with adequate hemodynamic tolerance. Since pirmenol is highly effective by both intravenous and oral routes, it enables immediate suppression, prevention, or termination of cardiac arrhythmias and facilitates the transition to oral prophylactic therapy.
• Uses: Cardiac depressant (anti-arrhythmic).