Flumeridone

Base Information

• Chemical Name: Flumeridone
• CAS No.: 75444-64-3
• Molecular Formula: C22H23 Cl F N5 O2
• Molecular Weight: 443.908
• European Community (EC) Number: 278-211-4
• UNII: 7ZZN46QU1N
• DSSTox Substance ID: DTXSID60226360
• Nikkaji Number: J307.572I
• Wikidata: Q27269094
• NCI Thesaurus Code: C65716
• Metabolomics Workbench ID: 155857
• ChEMBL ID: CHEMBL2107287
• Mol file: 75444-64-3.mol

Synonyms:Flumeridone;75444-64-3;Flumeridona;Flumeridonum;Flumeridonum [INN-Latin];UNII-7ZZN46QU1N;Flumeridona [INN-Spanish];7ZZN46QU1N;Flumeridone [USAN:INN:BAN];3-[3-[4-(5-chloro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-6-fluoro-1H-benzimidazol-2-one;EINECS 278-211-4;R-45,486;R 45486;R-45486;5-Chloro-1-(1-(3-(5-fluoro-2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone;2H-Benzimidazol-2-one, 1-(3-(4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl)propyl)-5-fluoro-1,3-dihydro-;5-Chloro-1-[1-[3-(5-fluoro-2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone;FLUMERIDONE [INN];Flumeridone (USAN/INN);FLUMERIDONE [USAN];C22H23ClFN5O2;SCHEMBL636160;Flumeridone [USAN:BAN:INN];CHEMBL2107287;DTXSID60226360;C22-H23-Cl-F-N5-O2;D04207;Q27269094;3-Azabicyclo[3.1.0]hexane-2,4-dione,1-(4-methylphenyl)-;1-[3-[4-[(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol)-1-yl]-1-piperidinyl]propyl]-5-fluoro-1,3-dihydro-2H-benzimidazol-2-one

Chemical Property of Flumeridone

Chemical Property:

• PSA: 78.82000
• Density: 1.38g/cm³
• LogP: 3.43020
• XLogP3: 4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 443.1524308
• Heavy Atom Count: 31
• Complexity: 691

Purity/Quality:

98%Min ^*data from raw suppliers

Flumeridone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=C(C=C(C=C5)F)NC4=O
• Uses: Anti-emetic. Flumeridone acts as one of the substances that assists in sickle cell formation inhibition by drugs in humans cells.

Technology Process of Flumeridone

There total 1 articles about Flumeridone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 5-chloro-1-{1-[3-(5-fluoro-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one (75444-64-3)

Guidance literature:

Aus dem entspr. Piperidin u. Propylchlorid;