Technology Process of 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[2-oxo-4-(phenylmethoxy)butyl]-
There total 4 articles about 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[2-oxo-4-(phenylmethoxy)butyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methylphosphonic acid; dimethyl sulfoxide; dicyclohexyl-carbodiimide;
for 20h;
Ambient temperature;
DOI:10.1021/jo00206a005
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) sodium hydride / 1.) DMF, RT, 1 h, 2.) 110 deg C, 24 h
2: 42 percent / DMSO, dicyclohexylcarbodiimide, methylphosphonic acid / 20 h / Ambient temperature
With
methylphosphonic acid; sodium hydride; dimethyl sulfoxide; dicyclohexyl-carbodiimide;
DOI:10.1021/jo00206a005
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) methanesulfonyl chloride, pyridine, 2.) NaOH / 1.) 0 deg C, 10 min, 2.) water, Me2SO, 0 deg C, 10 min
2: 1.) sodium hydride / 1.) DMF, RT, 1 h, 2.) 110 deg C, 24 h
3: 42 percent / DMSO, dicyclohexylcarbodiimide, methylphosphonic acid / 20 h / Ambient temperature
With
pyridine; sodium hydroxide; methylphosphonic acid; sodium hydride; dimethyl sulfoxide; methanesulfonyl chloride; dicyclohexyl-carbodiimide;
DOI:10.1021/jo00206a005
