Technology Process of 1,1-Cyclohexanedicarboxylic acid, 2-[(dimethylamino)methyl]-, dimethyl
ester
There total 7 articles about 1,1-Cyclohexanedicarboxylic acid, 2-[(dimethylamino)methyl]-, dimethyl
ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 60 percent / hydrogen / 5 percent palladium on barium sulfate / methanol
2: 1.) triethylamine, methanesulfonyl chloride; 2.) sodium iodide / 1.) THF, 0 deg C; 2.) acetone, ref.,
3: 2.) sodium hydride / 1.) THF, 0 deg C; 2.) THF, HMPA, 25 deg C
4: 1.) lithium tetrachloropalladate, molecular sieves (4 Angstroem); 2.) hydrogen / 1.) THF; 2.) THF
With
lithium pentachloropalladate; 4 A molecular sieve; hydrogen; sodium hydride; methanesulfonyl chloride; triethylamine; sodium iodide;
Pd-BaSO4;
In
methanol;
DOI:10.1021/ja00293a049
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 2.) sodium hydride / 1.) THF, 0 deg C; 2.) THF, HMPA, 25 deg C
2: 92 percent / hydrogen / 5 percent palladium on barium sulfate / methanol
3: 1.) lithium tetrachloropalladate, molecular sieves (4 Angstroem); 2.) hydrogen / 1.) THF; 2.) THF
With
lithium pentachloropalladate; 4 A molecular sieve; hydrogen; sodium hydride;
Pd-BaSO4;
In
methanol;
DOI:10.1021/ja00293a049
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 92 percent / hydrogen / 5 percent palladium on barium sulfate / methanol
2: 1.) lithium tetrachloropalladate, molecular sieves (4 Angstroem); 2.) hydrogen / 1.) THF; 2.) THF
With
lithium pentachloropalladate; 4 A molecular sieve; hydrogen;
Pd-BaSO4;
In
methanol;
DOI:10.1021/ja00293a049
