7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one

Base Information

Chemical Name:7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one
CAS No.:94527-34-1
Molecular Formula:C10H9NO3
Molecular Weight:191.186
Hs Code.:
DSSTox Substance ID:DTXSID60442043
Wikidata:Q82259105
Mol file:94527-34-1.mol

Synonyms:94527-34-1;7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one;1,3-Dioxolo[4,5-g]quinolin-6(5H)-one, 7,8-dihydro-;3,4-Dihydro-6,7-(methylenedioxy)-2(1H)-quinolinone;STK826163;7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-one;2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-6-one;SCHEMBL9092910;DTXSID60442043;AKOS005635870;FS-7721;6,7-methylenedioxy-1,2,3,4-tetrahydro-2-oxoquinoline;[1,3]Dioxolo[4,5-g]quinolin-6(5H)-one, 7,8-dihydro-

Suppliers and Price of 7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
3,4-Dihydro-6,7-(methylenedioxy)-2(1H)-quinolinone ≥98%
5mg
$ 312.00

American Custom Chemicals Corporation
7,8-DIHYDRO-1,3-DIOXOLO-[4,5-G]-QUINOLIN-6(5H)-ONE 95.00%
5MG
$ 503.73

Total 4 raw suppliers

Chemical Property of 7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one

Chemical Property:

PSA：51.05000
LogP:1.38510
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:191.058243149
Heavy Atom Count:14
Complexity:256

Purity/Quality:

98% ^*data from raw suppliers

3,4-Dihydro-6,7-(methylenedioxy)-2(1H)-quinolinone ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC2=CC3=C(C=C21)OCO3

Technology Process of 7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one

There total 1 articles about 7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1D-3,4,5-Tri-O-[3-(4,5-dimethylenedioxy-2-nitrophenyl)propanoyl]-myo-inositol 1,2,6-tris(ethoxycarbonyloxymethyl sodium phosphate)

: 94527-34-1
7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one

: 1D-myo-Inositol 1,2,6-tris(ethoxycarbonyloxymethyl sodium phosphate)

Guidance literature:: With hydrogen; palladium on activated charcoal; In acetic acid; at 20 ℃; for 20h; under 760 Torr;
DOI:10.1080/07328309608005673

Reference yield:

: 94527-34-1
7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one

: 1384850-36-5
3-[2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinolin-5-yl]-2-(4-fluorophenyl)quinoxaline-6-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: borane / tetrahydrofuran / 60 °C

1.2: Cooling

1.3: pH 8

2.1: 1-methyl-pyrrolidin-2-one / 1 h / 140 °C

3.1: pyridine / dichloromethane / 20 °C

4.1: potassium phosphate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 0.67 h / 90 °C / Inert atmosphere

5.1: sodium hydroxide; water / methanol / 20 °C

5.2: pH 5

With pyridine; potassium phosphate; borane; water; sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; 1-methyl-pyrrolidin-2-one; methanol; dichloromethane; water;

Reference yield:

: 94527-34-1
7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one

: 1384850-83-2
methyl 3-(7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-5(6H)-yl)-2-(4-fluorophenyl)quinoxaline-6-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: borane / tetrahydrofuran / 60 °C

1.2: Cooling

1.3: pH 8

2.1: 1-methyl-pyrrolidin-2-one / 1 h / 140 °C

3.1: pyridine / dichloromethane / 20 °C

4.1: potassium phosphate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 0.67 h / 90 °C / Inert atmosphere

With pyridine; potassium phosphate; borane; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; 1-methyl-pyrrolidin-2-one; dichloromethane; water;