Mitomycin D

Base Information

Chemical Name:Mitomycin D
CAS No.:10169-34-3
Molecular Formula:C15H18 N4 O5
Molecular Weight:334.332
Hs Code.:
UNII:ZVE62LIE63
ChEMBL ID:CHEMBL103528
Nikkaji Number:J247.884F
Mol file:10169-34-3.mol

Synonyms:mitomycin D;mitomycin D, (1aS-(1aalpha,8beta,8aalpha,8balpha))-isomer

Suppliers and Price of Mitomycin D

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Mitomycin D
1mg
$ 1936.00

American Custom Chemicals Corporation
MITOMYCIN D 95.00%
10MG
$ 750.75

AK Scientific
MitomycinD
5mg
$ 5371.00

Total 20 raw suppliers

Chemical Property of Mitomycin D

Chemical Property:

Vapor Pressure:5.47E-17mmHg at 25°C
Boiling Point:601.7°Cat760mmHg
Flash Point:317.7°C
PSA：138.96000
Density:1.64g/cm³
LogP:-0.68670
XLogP3:-0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:334.12771969
Heavy Atom Count:24
Complexity:772

Purity/Quality:

98%,99%, ^*data from raw suppliers

Mitomycin D ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)O)N4C)N
Isomeric SMILES:CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@H]2COC(=O)N)O)N4C)N
Uses As an antitumor antibiotic, mitomycin D is used as antineoplastic. An antitumor antibiotic. It is used as antineoplastic.

Technology Process of Mitomycin D

There total 5 articles about Mitomycin D which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 105616-80-6
10-O-decarbamoyl-10-O-<(trichloroacetyl)carbamoyl>mitomycin D

: 10169-34-3
mitomycin D

Guidance literature:: With potassium carbonate; In methanol; for 0.666667h; Ambient temperature;
DOI:10.1021/jo00286a021

Reference yield:

: 4055-40-7
mitomycin B

: 10169-34-3
mitomycin D

Guidance literature:: With ammonia; In methanol; for 6h; Ambient temperature;
DOI:10.1021/jo00032a037

Reference yield:

: 78879-23-9,78962-35-3
C₁₄H₁₇N₃O₄

: 10169-34-3
mitomycin D

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / CH₂Cl₂ / 0.33 h / 0 °C

2: 70 percent / K₂CO₃ / methanol / 0.67 h / Ambient temperature

With potassium carbonate; In methanol; dichloromethane;
DOI:10.1021/jo00286a021