1-((2-(diMethylaMino)ethyl)aMino)-7-hydroxy-4-(hydroxyMethyl)-9H-xanthen-9-one

Base Information

• Chemical Name: 1-((2-(diMethylaMino)ethyl)aMino)-7-hydroxy-4-(hydroxyMethyl)-9H-xanthen-9-one
• CAS No.: 86455-98-3
• Molecular Formula: C18H20N2O4
• Molecular Weight: 328.3624
• Hs Code.: 2932999099
• Mol file: 86455-98-3.mol

Synonyms:1-[2-(dimethylamino)ethylamino]-7-hydroxy-4-(hydroxymethyl)xanthen-9-one;

Chemical Property of 1-((2-(diMethylaMino)ethyl)aMino)-7-hydroxy-4-(hydroxyMethyl)-9H-xanthen-9-one

Chemical Property:

• Vapor Pressure: 4.25E-14mmHg at 25°C
• Boiling Point: 575.8°Cat760mmHg
• Flash Point: 302°C
• PSA: 85.94000
• Density: 1.356g/cm³
• LogP: 2.19060
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

97% ^*data from raw suppliers

1-((2-(Dimethylamino)ethyl)amino)-7-hydroxy-4-(hydroxymethyl)-9H-xanthen-9-one 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-((2-(diMethylaMino)ethyl)aMino)-7-hydroxy-4-(hydroxyMethyl)-9H-xanthen-9-one

There total 8 articles about 1-((2-(diMethylaMino)ethyl)aMino)-7-hydroxy-4-(hydroxyMethyl)-9H-xanthen-9-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

NSC 354677 (86456-22-6) → 1-[[2-(Dimethylamino)ethyl]amino]-7-hydroxy-4-(hydroxymethyl)-9H-xanthen-9-one (86455-98-3)

Guidance literature:

With potassium hydroxide; In ethanol; for 0.5h; Heating;

DOI:10.1021/jm00363a007

Reference yield:

3-iodochlorobenzene (625-99-0) → 1-[[2-(Dimethylamino)ethyl]amino]-7-hydroxy-4-(hydroxymethyl)-9H-xanthen-9-one (86455-98-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) K₂CO₃, 2.) Cu, CuI / 1.) DMF, 120 deg C, 10 min, 2.) DMF, reflux, 50 h

2: 1.) 50percent polyphosphoric acid, 2.) pyridine / 1.) 120 deg C, 3 h, 2.) reflux, 16 h

3: 87 percent / 56percent HI / 4 h / Heating

4: 92 percent / pyridine / 1.5 h / 50 °C

5: 46 percent / 5 N aq. acetic acid / 72 h / 70 °C

6: 88 percent / 5 N aq. KOH / ethanol / 0.5 h / Heating

With pyridine; potassium hydroxide; copper(l) iodide; PPA; hydrogen iodide; copper; potassium carbonate; acetic acid; In ethanol;

DOI:10.1021/jm00363a007

Reference yield:

5-methoxysalicylic acid (2612-02-4) → 1-[[2-(Dimethylamino)ethyl]amino]-7-hydroxy-4-(hydroxymethyl)-9H-xanthen-9-one (86455-98-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) K₂CO₃, 2.) Cu, CuI / 1.) DMF, 120 deg C, 10 min, 2.) DMF, reflux, 50 h

2: 1.) 50percent polyphosphoric acid, 2.) pyridine / 1.) 120 deg C, 3 h, 2.) reflux, 16 h

3: 87 percent / 56percent HI / 4 h / Heating

4: 92 percent / pyridine / 1.5 h / 50 °C

5: 46 percent / 5 N aq. acetic acid / 72 h / 70 °C

6: 88 percent / 5 N aq. KOH / ethanol / 0.5 h / Heating

With pyridine; potassium hydroxide; copper(l) iodide; PPA; hydrogen iodide; copper; potassium carbonate; acetic acid; In ethanol;

DOI:10.1021/jm00363a007

upstream raw materials:

NSC 354677

3-iodochlorobenzene

5-methoxysalicylic acid

2-(3-chlorophenoxy)-5-methoxybenzoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 86455-98-3 1-((2-(diMethylaMino)ethyl)aMino)-7-hydroxy-4-(hydroxyMethyl)-9H-xanthen-9-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send