2-o-Tolylamino-propionic acid

Base Information

Chemical Name:2-o-Tolylamino-propionic acid
CAS No.:94800-25-6
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:2922499990
DSSTox Substance ID:DTXSID10375276
Mol file:94800-25-6.mol

Synonyms:2-o-Tolylamino-propionic acid;94800-25-6;2-o-tolylamino propionic acid;2-(2-methylanilino)propanoic acid;2-(o-Tolylamino)propanoic acid;2-Methylphenyl-D-alanine;o-toluidinopropionic acid;2-o-tolylaminopropionic acid;2-(o-Tolylamino)propanoicacid;2-O-tolylamino propanoic acid;SCHEMBL7200135;DTXSID10375276;AKOS000101755;2-(2-TOLUIDINO)PROPANOIC ACID;FT-0693626

Suppliers and Price of 2-o-Tolylamino-propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(o-Tolylamino)propanoicacid 97%
1g
$ 589.00

American Custom Chemicals Corporation
2-ORTHO-TOLYLAMINO PROPIONIC ACID 98.00%
1G
$ 1083.39

AHH
2-o-Tolylaminopropionicacid 98%
1g
$ 280.00

Total 8 raw suppliers

Chemical Property of 2-o-Tolylamino-propionic acid

Chemical Property:

Boiling Point:365.7±25.0 °C(Predicted)
PKA:2.14±0.10(Predicted)
PSA：49.33000
Density:1.169±0.06 g/cm3(Predicted)
LogP:1.95300
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:182

Purity/Quality:

98%min ^*data from raw suppliers

2-(o-Tolylamino)propanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC(C)C(=O)O

Technology Process of 2-o-Tolylamino-propionic acid

There total 10 articles about 2-o-Tolylamino-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 95-49-8
2-methylchlorobenzene

: 302-72-7,25191-17-7,18875-37-1
rac-Ala-OH

: 94800-25-6
N-(2-methylphenyl)alanine

Guidance literature:: With di-tert-butyl{2′-isopropoxy-[1,1′-binaphthalen]-2-yl}phosphane; potassium hydroxide; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tert-butyl alcohol; at 90 ℃; for 20h; Inert atmosphere;
DOI:10.1016/j.tet.2011.09.109

Reference yield: 86.0%

: 95-46-5
2-methylphenyl bromide

: 302-72-7,25191-17-7,18875-37-1
rac-Ala-OH

: 94800-25-6
N-(2-methylphenyl)alanine

Guidance literature:: With di-tert-butyl{2′-isopropoxy-[1,1′-binaphthalen]-2-yl}phosphane; potassium hydroxide; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tert-butyl alcohol; at 90 ℃; for 20h; Inert atmosphere;
DOI:10.1016/j.tet.2011.09.109

Reference yield:

: 95-53-4
o-toluidine

: 94800-25-6
N-(2-methylphenyl)alanine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium acetate trihydrate / ethanol / 24 h / Heating

2: 10percent aq. NaOH / 2 h / Heating

With sodium hydroxide; sodium acetate; In ethanol;
DOI:10.1021/je00040a036