Pentanoic acid, 4-[[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]amino]-5-[( 2-methylpropyl)amino]-5-oxo-, 1,1-dimethylethyl ester, (S)-

Base Information

Chemical Name:Pentanoic acid, 4-[[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]amino]-5-[( 2-methylpropyl)amino]-5-oxo-, 1,1-dimethylethyl ester, (S)-
CAS No.:95064-27-0
Molecular Formula:C₂₈H₃₉N₉O₄
Molecular Weight:565.676
Hs Code.:

Pentanoic acid,
4-[[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]amino]-5-[(
2-methylpropyl)amino]-5-oxo-, 1,1-dimethylethyl ester, (S)-

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pentanoic acid, 4-[[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]amino]-5-[( 2-methylpropyl)amino]-5-oxo-, 1,1-dimethylethyl ester, (S)-

Chemical Property:

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Technology Process of Pentanoic acid, 4-[[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]amino]-5-[( 2-methylpropyl)amino]-5-oxo-, 1,1-dimethylethyl ester, (S)-

There total 5 articles about Pentanoic acid, 4-[[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]amino]-5-[( 2-methylpropyl)amino]-5-oxo-, 1,1-dimethylethyl ester, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 540-88-5
acetic acid tert-butyl ester

: 95064-27-0
(S)-4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-4-isobutylcarbamoyl-butyric acid tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

2: H₂ / palladium-charcoal / methanol

3: triethylamine / dioxane / 1 h

4: aq. triethylamine / methanol / Heating

5: dimethylformamide / 2.5 h / 65 - 70 °C

With hydrogen; triethylamine; palladium on activated charcoal; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;

Reference yield:

: 95063-75-5
(S)-4-Benzyloxycarbonylamino-4-isobutylcarbamoyl-butyric acid tert-butyl ester

: 95064-27-0
(S)-4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-4-isobutylcarbamoyl-butyric acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / palladium-charcoal / methanol

2: triethylamine / dioxane / 1 h

3: aq. triethylamine / methanol / Heating

4: dimethylformamide / 2.5 h / 65 - 70 °C

With hydrogen; triethylamine; palladium on activated charcoal; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;

Reference yield:

: (S)-4-Amino-4-isobutylcarbamoyl-butyric acid tert-butyl ester

: 95064-27-0
(S)-4-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-4-isobutylcarbamoyl-butyric acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dioxane / 1 h

2: aq. triethylamine / methanol / Heating

3: dimethylformamide / 2.5 h / 65 - 70 °C

With triethylamine; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;