Pyroglutamylvaline

Base Information

Chemical Name:Pyroglutamylvaline
CAS No.:21282-10-0
Molecular Formula:C₁₀H₁₆N₂O₄
Molecular Weight:228.248
Hs Code.:
DSSTox Substance ID:DTXSID40175549
Nikkaji Number:J364.501K
Wikidata:Q83045914
Metabolomics Workbench ID:71627
Mol file:21282-10-0.mol

Synonyms:pyro-Glu-Val;pyroglutamyl valine;pyroglutamylvaline

Suppliers and Price of Pyroglutamylvaline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chem-Impex
Pyr-Val-OH
250MG
$ 186.37

Chem-Impex
Pyr-Val-OH
100MG
$ 99.01

Total 7 raw suppliers

Chemical Property of Pyroglutamylvaline

Chemical Property:

Vapor Pressure:4.75E-15mmHg at 25°C
Boiling Point:581.9°Cat760mmHg
Flash Point:305.7°C
PSA：95.50000
Density:1.249g/cm³
LogP:0.21010
XLogP3:-0.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:228.11100700
Heavy Atom Count:16
Complexity:314

Purity/Quality:

95% ^*data from raw suppliers

Pyr-Val-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)O)NC(=O)C1CCC(=O)N1
Isomeric SMILES:CC(C)[C@@H](C(=O)O)NC(=O)[C@@H]1CCC(=O)N1

Technology Process of Pyroglutamylvaline

There total 3 articles about Pyroglutamylvaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: C₁₉H₃₂N₂O₆

: 21282-10-0,20760-74-1
L-pyroglutamyl-valine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 3h;
DOI:10.1016/j.lfs.2014.08.017

Reference yield:

: 13518-40-6
L-valine tert-butylester hydrochloride

: 53100-44-0,160347-90-0
L-N-t-butoxycarbonylpyroglutamic acid

: 21282-10-0,20760-74-1
L-pyroglutamyl-valine

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 12 h / 0 - 20 °C

2: hydrogenchloride / 1,4-dioxane / 3 h / 20 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1016/j.lfs.2014.08.017