Technology Process of Pyrido[3,2-d]pyrimidine-2,4-diamine, 6-[(4-chlorophenyl)sulfonyl]-,
1,5-dioxide
There total 6 articles about Pyrido[3,2-d]pyrimidine-2,4-diamine, 6-[(4-chlorophenyl)sulfonyl]-,
1,5-dioxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dihydrogen peroxide; trifluoroacetic anhydride;
In
dichloromethane;
for 21h;
Ambient temperature;
DOI:10.1002/jhet.5570210556
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 58 percent / various solvent(s) / 0.25 h / 178 - 182 °C
2: 62 percent / Potassium carbonate / acetone / 0.25 h / 0 - 10 °C
3: 42 percent / conc.HCl,iron powder / methanol / 2 h / Heating
4: 40 percent / various solvent(s) / 1.5 h / 145 - 165 °C
5: 49 percent / 30percentH2O2,acetic acid / 41 h / Ambient temperature
6: 40 percent / 30percentH2O2,trifluoroacetic anhydride / CH2Cl2 / 21 h / Ambient temperature
With
hydrogenchloride; dihydrogen peroxide; iron; potassium carbonate; acetic acid; trifluoroacetic anhydride;
In
methanol; dichloromethane; acetone;
DOI:10.1002/jhet.5570210556
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 62 percent / Potassium carbonate / acetone / 0.25 h / 0 - 10 °C
2: 42 percent / conc.HCl,iron powder / methanol / 2 h / Heating
3: 40 percent / various solvent(s) / 1.5 h / 145 - 165 °C
4: 49 percent / 30percentH2O2,acetic acid / 41 h / Ambient temperature
5: 40 percent / 30percentH2O2,trifluoroacetic anhydride / CH2Cl2 / 21 h / Ambient temperature
With
hydrogenchloride; dihydrogen peroxide; iron; potassium carbonate; acetic acid; trifluoroacetic anhydride;
In
methanol; dichloromethane; acetone;
DOI:10.1002/jhet.5570210556
