2-Naphthalenepropanenitrile

Base Information

• Chemical Name: 2-Naphthalenepropanenitrile
• CAS No.: 95104-51-1
• Molecular Formula: C13H11N
• Molecular Weight: 181.237
• Mol file: 95104-51-1.mol

Synonyms:

Chemical Property of 2-Naphthalenepropanenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Naphthalenepropanenitrile

There total 2 articles about 2-Naphthalenepropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

2-Naphthalenemethanol (1592-38-7) + cyanomethylene triphenylphosphorane (16640-68-9) → 3-(naphthalen-2-yl)propanenitrile (95104-51-1) + β-naphthaldehyde (66-99-9) + (E)-3-(naphthalen-2-yl)-2-propenenitrile

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; 1,3-bis-(diphenylphosphino)propane; caesium carbonate; In toluene; at 150 ℃; for 72h;

DOI:10.1002/anie.200290034

Reference yield: 46.0%

2-Naphthalenemethanol (1592-38-7) + cyanomethylene triphenylphosphorane (16640-68-9) → 2,2'-oxybis(methylene)dinaphthalene (55644-75-2) + 3-(naphthalen-2-yl)propanenitrile (95104-51-1) + β-naphthaldehyde (66-99-9) + 2-Methylnaphthalene (91-57-6,34468-07-0)

Guidance literature:

With 1,3-bis-(diphenylphosphino)propane; caesium carbonate; bis(1,5-cyclooctadiene)diiridium(I) dichloride; In toluene; at 150 ℃; for 72h; Further byproducts given;

DOI:10.1002/ejoc.200600070

Reference yield: 99.0%

3-(naphthalen-2-yl)propanenitrile (95104-51-1) + Diphenylphosphine oxide (4559-70-0) → (2-(naphthalen-2-yl)ethyl)diphenylphosphine oxide

Guidance literature:

With potassium tert-butylate; nickel dichloride; In 1,4-dioxane; at 120 ℃; for 16h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.8b02854

upstream raw materials:

2-Naphthalenemethanol

cyanomethylene triphenylphosphorane

Downstream raw materials:

3-(naphthalen-2-yl)propanal