4-(4-oxo-3,4-dihydroquinazolin-2-yl)butanoic acid(SALTDATA: FREE)

Base Information

Chemical Name:4-(4-oxo-3,4-dihydroquinazolin-2-yl)butanoic acid(SALTDATA: FREE)
CAS No.:95494-51-2
Molecular Formula:C12H12N2O3
Molecular Weight:232.239
Hs Code.:2933990090
Mol file:95494-51-2.mol

Synonyms:3,4-dihydro-4-oxoquinazoline-2-butyric acid;

Suppliers and Price of 4-(4-oxo-3,4-dihydroquinazolin-2-yl)butanoic acid(SALTDATA: FREE)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(4-Oxo-3,4-dihydroquinazolin-2-yl)butanoic acid
500mg
$ 293.00

Crysdot
4-(4-Oxo-3,4-dihydroquinazolin-2-yl)butanoicacid 95+%
5g
$ 844.00

Chemenu
4-(4-oxo-3,4-dihydroquinazolin-2-yl)butanoicacid 95%
5g
$ 863.00

American Custom Chemicals Corporation
4-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)BUTANOIC ACID 95.00%
1G
$ 794.34

American Custom Chemicals Corporation
4-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)BUTANOIC ACID 95.00%
5G
$ 1379.44

American Custom Chemicals Corporation
4-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)BUTANOIC ACID 95.00%
2.5G
$ 1119.71

Alichem
4-(4-Oxo-3,4-dihydroquinazolin-2-yl)butanoicacid
5g
$ 903.12

AK Scientific
4-(4-Oxo-3,4-dihydroquinazolin-2-yl)butanoicacid
250mg
$ 493.00

Total 9 raw suppliers

Chemical Property of 4-(4-oxo-3,4-dihydroquinazolin-2-yl)butanoic acid(SALTDATA: FREE)

Chemical Property:

PSA：83.05000
LogP:1.33040
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4-(4-Oxo-3,4-dihydroquinazolin-2-yl)butanoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-(4-oxo-3,4-dihydroquinazolin-2-yl)butanoic acid(SALTDATA: FREE)

There total 2 articles about 4-(4-oxo-3,4-dihydroquinazolin-2-yl)butanoic acid(SALTDATA: FREE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.3%

: 108-55-4
glutaric anhydride,

: 28144-70-9,88-68-6
anthranilic acid amide

: 95494-51-2
4-(4-oxo-3,4-dihydro-quinazolin-2-yl)-butyric acid

Guidance literature:: In toluene; for 3h; Reflux;

Reference yield:

: 28144-70-9,88-68-6
anthranilic acid amide

: 95494-51-2
4-(4-oxo-3,4-dihydro-quinazolin-2-yl)-butyric acid

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether; benzene; 1,4-dioxane / 2 h / 20 °C

2: sodium hydroxide / ethanol; water / 0.5 h

With sodium hydroxide; In 1,4-dioxane; diethyl ether; ethanol; water; benzene;
DOI:10.1016/j.bioorg.2016.07.001

Reference yield: 79.0%

: 328-74-5
3,5-Bis-(trifluoromethyl)aniline

: 95494-51-2
4-(4-oxo-3,4-dihydro-quinazolin-2-yl)-butyric acid

: N-(3,5-bis(trifluoromethyl)phenyl)-4-(4-oxo-3,4-dihydroquinazolin-2-yl)butanamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 14h; Inert atmosphere; Schlenk technique;
DOI:10.1016/j.bioorg.2019.103352