N-Aminodiphenylhydantoin

Base Information

• Chemical Name: N-Aminodiphenylhydantoin
• CAS No.: 1224-08-4
• Molecular Formula: C15H13 N3 O2
• Molecular Weight: 267.287
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID10153591
• Nikkaji Number: J77.695E
• Wikidata: Q83020538
• ChEMBL ID: CHEMBL1725368
• Mol file: 1224-08-4.mol

Synonyms:3-amino-DPH;3-aminodiphenylhydantoin;N-aminodiphenylhydantoin

Chemical Property of N-Aminodiphenylhydantoin

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 78.92000
• Density: 1.315g/cm³
• LogP: 1.63390
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 267.100776666
• Heavy Atom Count: 20
• Complexity: 380

Purity/Quality:

97% ^*data from raw suppliers

3-Amino-5,5-diphenylimidazolidine-2,4-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2(C(=O)N(C(=O)N2)N)C3=CC=CC=C3

Technology Process of N-Aminodiphenylhydantoin

There total 10 articles about N-Aminodiphenylhydantoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

ethyl 3-(5,5-diphenylhydantoin) formate (1097-57-0) → 3-amino-5,5-diphenylimidazolidine-2,4-dione (1224-08-4) + phenythoin (57-41-0)

Guidance literature:

With hydrazine hydrate; at 130 - 140 ℃; for 4h;

Reference yield: 86.0%

phenythoin (57-41-0) → 3-amino-5,5-diphenylimidazolidine-2,4-dione (1224-08-4)

Guidance literature:

With hydrazine hydrate; In methanol; for 12h; Reflux;

DOI:10.1016/j.ejmech.2016.03.011

Reference yield: 56.0%

ethyl 2-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)acetate (976-85-2) → 3-amino-5,5-diphenylimidazolidine-2,4-dione (1224-08-4)

Guidance literature:

With hydrazine hydrate; at 130 - 140 ℃; for 4h;

upstream raw materials:

ethyl 2-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)acetate

phenythoin

ethyl 3-(5,5-diphenylhydantoin) formate

hydrazine carboxamide