Technology Process of L-Proline, 5-butyl-1-(phenylmethyl)-, cis-
There total 5 articles about L-Proline, 5-butyl-1-(phenylmethyl)-, cis- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; acetic acid;
In
propan-1-ol;
for 6h;
Heating;
DOI:10.1021/jo00208a016
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 96 percent / ammonium formate, acetic acid / 10percent Pd/C / methanol / 1.5 h / Irradiation
2: 92 percent / calcined K2CO3 / acetonitrile / 1.) 0 deg C, 30 min, 2.) RT, 16 h
3: 81 percent / acetic acid, water / propan-1-ol / 6 h / Heating
With
calcined K2CO3; water; ammonium formate; acetic acid;
palladium on activated charcoal;
In
methanol; propan-1-ol; acetonitrile;
DOI:10.1021/jo00208a016
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) triphenylphosphine, 2.) 1-methylpiperidine / 1.) CH2Cl2, 30 min, 2.) 0 deg C, 5 h
2: 96 percent / ammonium formate, acetic acid / 10percent Pd/C / methanol / 1.5 h / Irradiation
3: 92 percent / calcined K2CO3 / acetonitrile / 1.) 0 deg C, 30 min, 2.) RT, 16 h
4: 81 percent / acetic acid, water / propan-1-ol / 6 h / Heating
With
N-methylcyclohexylamine; calcined K2CO3; water; ammonium formate; acetic acid; triphenylphosphine;
palladium on activated charcoal;
In
methanol; propan-1-ol; acetonitrile;
DOI:10.1021/jo00208a016
