1-Oxa-3,9-diazaspiro(5.5)undecan-2-one, 5-ethyl-9-(3-(p-fluorobenzoyl)propyl)-

Base Information

Chemical Name:1-Oxa-3,9-diazaspiro(5.5)undecan-2-one, 5-ethyl-9-(3-(p-fluorobenzoyl)propyl)-
CAS No.:54981-17-8
Molecular Formula:C20H27FN2O3
Molecular Weight:362.4384
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90970329
Mol file:54981-17-8.mol

Synonyms:54981-17-8;BRN 0566898;1-Oxa-3,9-diazaspiro(5.5)undecan-2-one, 5-ethyl-9-(3-(p-fluorobenzoyl)propyl)-;DTXSID90970329;Oxo-2 ethyl-5 ((fluoro-4 benzoyl)-3 propyl)-9 oxadiaza-1,3,9 spiro(5,5)undecane [French];Oxo-2 ethyl-5 ((fluoro-4 benzoyl)-3 propyl)-9 oxadiaza-1,3,9 spiro(5,5)undecane;4-(4-Ethyl-2-hydroxy-1-oxa-3,9-diazaspiro[5.5]undec-2-en-9-yl)-1-(4-fluorophenyl)butan-1-one

Suppliers and Price of 1-Oxa-3,9-diazaspiro(5.5)undecan-2-one, 5-ethyl-9-(3-(p-fluorobenzoyl)propyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Oxa-3,9-diazaspiro(5.5)undecan-2-one, 5-ethyl-9-(3-(p-fluorobenzoyl)propyl)-

Chemical Property:

Vapor Pressure:2.73E-13mmHg at 25°C
Boiling Point:576.5°Cat760mmHg
Flash Point:302.4°C
PSA：62.13000
Density:1.2g/cm³
LogP:3.10960
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:362.20057089
Heavy Atom Count:26
Complexity:497

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1CC2(CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)OC(=O)N1

Technology Process of 1-Oxa-3,9-diazaspiro(5.5)undecan-2-one, 5-ethyl-9-(3-(p-fluorobenzoyl)propyl)-

There total 2 articles about 1-Oxa-3,9-diazaspiro(5.5)undecan-2-one, 5-ethyl-9-(3-(p-fluorobenzoyl)propyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 54981-03-2
4-(1-aminomethyl-propyl)-1-benzyl-piperidin-4-ol

: 54981-17-8
5-ethyl-9-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-oxa-3,9-diaza-spiro[5.5]undecan-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: aq. KOH / toluene

2: H₂ / Pd-C / aq. ethanol

3: Na₂CO₃, KI / toluene

With potassium hydroxide; hydrogen; sodium carbonate; potassium iodide; palladium on activated charcoal; In ethanol; toluene;

Reference yield:

: 54981-08-7
9-benzyl-5-ethyl-1-oxa-3,9-diaza-spiro[5.5]undecan-2-one

: 54981-17-8
5-ethyl-9-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-oxa-3,9-diaza-spiro[5.5]undecan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd-C / aq. ethanol

2: Na₂CO₃, KI / toluene

With hydrogen; sodium carbonate; potassium iodide; palladium on activated charcoal; In ethanol; toluene;