5-bromo-3-hydroxy-4H-pyran-4-one

Base Information

Chemical Name:5-bromo-3-hydroxy-4H-pyran-4-one
CAS No.:95790-60-6
Molecular Formula:C5H3BrO3
Molecular Weight:190.98000
Hs Code.:
European Community (EC) Number:828-828-5
Mol file:95790-60-6.mol

Synonyms:95790-60-6;3-bromo-5-hydroxy-4H-pyran-4-one;5-bromo-3-hydroxy-4H-pyran-4-one;4H-Pyran-4-one, 3-bromo-5-hydroxy-;3-BROMO-5-HYDROXYPYRAN-4-ONE;3-bromo-5-hydroxypyrane-4-one;SCHEMBL16921616;WZAIXBNVCZNFLR-UHFFFAOYSA-N;MFCD22062349;AKOS016353062;CS-0246419;EN300-325758

Suppliers and Price of 5-bromo-3-hydroxy-4H-pyran-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 5-bromo-3-hydroxy-4H-pyran-4-one

Chemical Property:

Melting Point:148 - 150 °C
PSA：50.44000
LogP:1.10790
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:189.92656
Heavy Atom Count:9
Complexity:204

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C(=O)C(=CO1)Br)O

Technology Process of 5-bromo-3-hydroxy-4H-pyran-4-one

There total 1 articles about 5-bromo-3-hydroxy-4H-pyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 60845-12-7,75282-82-5
4,5-epoxy-4-bromo-6-methoxytetrahydro-pyran-3-one

: 95790-60-6
5-bromo-3-hydroxy-4H-pyran-4-one

Guidance literature:: With sulfuric acid; at 90 - 95 ℃;
DOI:10.3987/COM-92-6090

Reference yield: 84.0%

: 100-44-7
benzyl chloride

: 95790-60-6
5-bromo-3-hydroxy-4H-pyran-4-one

: 152804-75-6
3-benzyloxy-5-bromo-4H-pyran-4-one

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 80 - 90 ℃;
DOI:10.3987/COM-93-6364

Reference yield:

: 95790-60-6
5-bromo-3-hydroxy-4H-pyran-4-one

: 3-Hydroxy-5-phenyl-pyran-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / 60percent NaH / dimethylformamide / 80 - 90 °C

2: 1.) tetrakis(triphenylphosphine)palladium(O), aq. 2M Na₂CO₃, 2.) 30percent aq. H₂O₂ / 1.) DME, reflux, 6 h, 2.) 30 min

3: 88 percent / aq. conc. HCl / acetic acid / 1 h / 90 - 100 °C

With hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; dihydrogen peroxide; sodium hydride; sodium carbonate; In acetic acid; N,N-dimethyl-formamide;
DOI:10.3987/COM-93-6364