alpha-Methyl-3-(4-methylphenyl)-2H-1,4-benzoxazine-6-acetic acid

Base Information

Chemical Name:alpha-Methyl-3-(4-methylphenyl)-2H-1,4-benzoxazine-6-acetic acid
CAS No.:86818-31-7
Molecular Formula:C₁₈H₁₇NO₃
Molecular Weight:295.338
Hs Code.:
DSSTox Substance ID:DTXSID101007113
Mol file:86818-31-7.mol

Synonyms:BRN 4522299;86818-31-7;alpha-Methyl-3-(4-methylphenyl)-2H-1,4-benzoxazine-6-acetic acid;2H-1,4-Benzoxazine-6-acetic acid, alpha-methyl-3-(4-methylphenyl)-;2-[3-(4-methylphenyl)-2H-1,4-benzoxazin-6-yl]propanoic acid;DTXSID101007113;LS-41677

Suppliers and Price of alpha-Methyl-3-(4-methylphenyl)-2H-1,4-benzoxazine-6-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ALPHA-METHYL-3-(4-METHYLPHENYL)-2H-1,4-BENZOXAZINE-6-ACETIC ACID 95.00%
5MG
$ 498.96

Total 3 raw suppliers

Chemical Property of alpha-Methyl-3-(4-methylphenyl)-2H-1,4-benzoxazine-6-acetic acid

Chemical Property:

Vapor Pressure:9.12E-10mmHg at 25°C
Boiling Point:473.4°Cat760mmHg
Flash Point:240.1°C
PSA：58.89000
Density:1.22g/cm³
LogP:3.13190
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:295.12084340
Heavy Atom Count:22
Complexity:440

Purity/Quality:: ALPHA-METHYL-3-(4-METHYLPHENYL)-2H-1,4-BENZOXAZINE-6-ACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC3=C(C=CC(=C3)C(C)C(=O)O)OC2

Technology Process of alpha-Methyl-3-(4-methylphenyl)-2H-1,4-benzoxazine-6-acetic acid

There total 3 articles about alpha-Methyl-3-(4-methylphenyl)-2H-1,4-benzoxazine-6-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 2-(3-p-Tolyl-2H-benzo[1,4]oxazin-6-yl)-propionic acid ethyl ester

: 86818-31-7
2-(3-p-Tolyl-2H-benzo[1,4]oxazin-6-yl)-propionic acid

Guidance literature:: With sulfuric acid; Heating;

Reference yield:

: 619-41-0
4-(bromoacetyl)toluene

: 86818-31-7
2-(3-p-Tolyl-2H-benzo[1,4]oxazin-6-yl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / K₂CO₃ / acetone / Heating

2: 64 percent / 20percent H₂SO₄ / Heating

With sulfuric acid; potassium carbonate; In acetone;

Reference yield:

: 51234-45-8
ethyl 2-(3-amino-4-hydroxyphenyl)-propionate

: 86818-31-7
2-(3-p-Tolyl-2H-benzo[1,4]oxazin-6-yl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / K₂CO₃ / acetone / Heating

2: 64 percent / 20percent H₂SO₄ / Heating

With sulfuric acid; potassium carbonate; In acetone;