2-Methyl-2-hexanamine

Base Information

• Chemical Name: 2-Methyl-2-hexanamine
• CAS No.: 2626-64-4
• Molecular Formula: C₇H₁₇N
• Molecular Weight: 115.219
• Hs Code.: 2921199090
• Mol file: 2626-64-4.mol

Synonyms:Pentylamine,1,1-dimethyl- (6CI,7CI); 1,1-Dimethylpentylamine; a,a-Dimethylpentylamine

Chemical Property of 2-Methyl-2-hexanamine

Chemical Property:

• Vapor Pressure: 7.29mmHg at 25°C
• Boiling Point: 136.7°Cat760mmHg
• Flash Point: 30.6°C
• PSA: 26.02000
• Density: 0.779g/cm³
• LogP: 2.61420

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Methyl-2-hexanamine

There total 8 articles about 2-Methyl-2-hexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2-methyl-2-azidohexane (76613-34-8) → 2-Amino-2-methyl-hexan (2626-64-4)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; 1.) 12 h, 2.) reflux, 1 h;

DOI:10.1021/jo00323a021

Reference yield:

2-methylhexan-2-ol (625-23-0) → 2-Amino-2-methyl-hexan (2626-64-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide 57percent aq. H₂SO₄ / CHCl₃ / 48 h / ice-bath

2: 88 percent / lithium aluminum hydride / diethyl ether / 1.) 12 h, 2.) reflux, 1 h

With lithium aluminium tetrahydride; sodium azide; sulfuric acid; In diethyl ether; chloroform;

DOI:10.1021/jo00323a021

Reference yield:

C8H15NO → 2-Amino-2-methyl-hexan (2626-64-4)

Guidance literature:

C₈H₁₅NO; With hydrogenchloride; In water; acetic acid; at 20 ℃;

With sodium hydroxide; In water;

DOI:10.1002/chem.201502621

upstream raw materials:

2-amino-2-methyl-hexan-3-ol

(1,1-dimethylpent-1-yl)urea

n-butyllithium

N-Isopropylidene-benzenesulfenamide

Downstream raw materials:

N-(1,1-dimethyl-pentyl)-N'-phenyl-urea

Refernces

• 1、 Ling, Peng-Xiang,Fang, Sheng-Long,Yin, Xue-Song,Chen, Kai,Sun, Bo-Zheng,Shi, Bing-Feng. "Palladium-Catalyzed Arylation of Unactivated γ-Methylene C(sp3)-H and δ-C-H Bonds with an Oxazoline-Carboxylate Auxiliary". . p. 17503 - 17507. Retrieved 2016/01/25.