4H-1-Benzopyran-4-one, 2-[2,5-dimethoxy-4-(1-methylethoxy)phenyl]-6-methoxy-5,7-bis(1-methyl ethoxy)-

Base Information

• Chemical Name: 4H-1-Benzopyran-4-one, 2-[2,5-dimethoxy-4-(1-methylethoxy)phenyl]-6-methoxy-5,7-bis(1-methyl ethoxy)-
• CAS No.: 96410-32-1
• Molecular Formula: C₂₇H₃₄O₈
• Molecular Weight: 486.562
• Mol file: 96410-32-1.mol

Synonyms:

Chemical Property of 4H-1-Benzopyran-4-one, 2-[2,5-dimethoxy-4-(1-methylethoxy)phenyl]-6-methoxy-5,7-bis(1-methyl ethoxy)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4H-1-Benzopyran-4-one, 2-[2,5-dimethoxy-4-(1-methylethoxy)phenyl]-6-methoxy-5,7-bis(1-methyl ethoxy)-

There total 8 articles about 4H-1-Benzopyran-4-one, 2-[2,5-dimethoxy-4-(1-methylethoxy)phenyl]-6-methoxy-5,7-bis(1-methyl ethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-dimethoxyphenol (18113-18-3) → 4',5,7-triisopropyloxy-2',5',6-trimethoxyflavone (96410-32-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 3.5 g / K₂CO₃ / dimethylformamide

2: 3.4 g / POCl₃

3: 1.2 g

4: 0.36 g / DDQ

With potassium carbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; trichlorophosphate; In N,N-dimethyl-formamide;

DOI:10.1248/cpb.32.4935

Reference yield:

2'-hydroxy-4,4',6'-triisopropyloxy-2,5,5'-trimethoxychalcone (96410-31-0) → 4',5,7-triisopropyloxy-2',5',6-trimethoxyflavone (96410-32-1)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone;

DOI:10.1248/cpb.32.4935

Reference yield:

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) → 4',5,7-triisopropyloxy-2',5',6-trimethoxyflavone (96410-32-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 11.5 g

2: 4.6 g / K₂S₂O₈

3: 1.9 g / partial methylation

4: 1.2 g

5: 0.36 g / DDQ

With dipotassium peroxodisulfate; 2,3-dicyano-5,6-dichloro-p-benzoquinone;

DOI:10.1248/cpb.32.4935

upstream raw materials:

2'-hydroxy-4,4',6'-triisopropyloxy-2,5,5'-trimethoxychalcone

2,5-dimethoxyphenol

2,4,6-trihydroxyacetophenone

1-(2-hydroxy-4,6-diisopropoxyphenyl)ethan-1-one

Downstream raw materials:

4',5,7-trihydroxy-2',5',6-trimethoxyflavone

Refernces