1-hydroxylamino-2-phenylethane

Base Information

• Chemical Name: 1-hydroxylamino-2-phenylethane
• CAS No.: 3217-93-4
• Molecular Formula: C8H11 N O
• Molecular Weight: 137.181
• Hs Code.: 2928000090
• Mol file: 3217-93-4.mol

Synonyms:Hydroxylamine,N-phenethyl- (6CI,7CI,8CI); N-Hydroxy-2-phenylethanamine;N-Hydroxyphenethylamine

Chemical Property of 1-hydroxylamino-2-phenylethane

Chemical Property:

• Vapor Pressure: 0.00338mmHg at 25°C
• Boiling Point: 270.4°Cat760mmHg
• Flash Point: 132.4°C
• PSA: 32.26000
• Density: 1.066g/cm³
• LogP: 1.59880

Purity/Quality:

N-(2-phenylethyl)hydroxylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-hydroxylamino-2-phenylethane

There total 16 articles about 1-hydroxylamino-2-phenylethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-phenyl-2-bromoethane (103-63-9) → N-phenylethylhydroxylamine (3217-93-4)

Guidance literature:

With hydroxylamine monohydrate; In methanol; at 100 ℃; for 0.166667h; under 18100.7 Torr; chemoselective reaction; Flow reactor;

DOI:10.1021/acs.joc.8b02387

Reference yield: 95.0%

phenethylamine (64-04-0) → N-phenylethylhydroxylamine (3217-93-4)

Guidance literature:

With urea hydrogen peroxide adduct; In diethyl ether; at 20 ℃; for 1h; Solvent; Temperature; Catalytic behavior; Inert atmosphere;

DOI:10.1039/d0nj00829j

Reference yield: 88.0%

2-phenethyl iodide (17376-04-4) → N-phenylethylhydroxylamine (3217-93-4)

Guidance literature:

With hydroxylamine monohydrate; In methanol; at 100 ℃; for 0.166667h; under 18100.7 Torr; chemoselective reaction; Flow reactor;

DOI:10.1021/acs.joc.8b02387

upstream raw materials:

(2-nitroethenyl)benzene

Phenylacetaldehyde oxime

phenethylamine

C₁₀H₁₀N₂O

Downstream raw materials:

α-(p-nitrophenyl)-N-(2-phenylethyl)nitrone

N-hydroxy-N-(2-phenylethyl)benzamide

N-β-Phenethyl-N-formylhydroxylamin

C₄₃H₇₁NO₃Si₂

Refernces

• 1、 Bahadorikhalili, Saeed,Arshadi, Hosein,Afrouzandeh, Zahra,Ma'mani, Leila. "Ultrasonic promoted synthesis of Ag nanoparticle decorated thiourea-functionalized magnetic hydroxyapatite: A robust inorganic-organic hybrid nanocatalyst for oxidation and reduction reactions". . p. 8840 - 8848. Retrieved 2020/06/08.
• 2、 -. "Primary hydroxylamines and uses thereof". Paragraph 0056; 0057; 0061. . Retrieved 2015/09/22.