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Technology Process of CHOLERA TOXIN

CHOLERA TOXIN

Base Information
  • Chemical Name:CHOLERA TOXIN
  • CAS No.:9012-63-9
  • Molecular Formula:NULL
  • Molecular Weight:0
  • Hs Code.:
CHOLERA TOXIN

Synonyms:Choleratoxin; Cholera toxins; Choleragen; Choleragenoid; Toxins, exo-, cholera

Suppliers and Price of CHOLERA TOXIN
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Cholera Toxin
  • 100ug
  • $ 478.00
  • Sigma-Aldrich
  • Cholera Toxin from Vibrio cholerae ≥90% (SDS-PAGE), lyophilized powder
  • 0.5 mg
  • $ 140.00
  • Sigma-Aldrich
  • Cholera Toxin from Vibrio cholerae ~95% (SDS-PAGE)
  • .5mg
  • $ 135.00
  • Sigma-Aldrich
  • Cholera Toxin from Vibrio cholerae ~95% (SDS-PAGE)
  • 1mg
  • $ 243.00
  • Sigma-Aldrich
  • CholeraToxin,Vibriocholerae,TypeInaba569B,AzideFree-CAS9012-63-9-Calbiochem CholeratoxinInaba569B,CAS9012-63-9,hasasingleAsubunitsurroundedbyfi
  • 1 mg
  • $ 230.32
  • Sigma-Aldrich
  • Cholera Toxin from Vibrio cholerae ~95% (SDS-PAGE)
  • 2mg
  • $ 441.00
  • ChemScene
  • Choleratoxin
  • 1mg
  • $ 750.00
  • Cayman Chemical
  • Cholera Toxin from Vibrio cholerae ≥95% (estimated by SDS-PAGE)
  • 1mg
  • $ 188.00
  • Cayman Chemical
  • Cholera Toxin from Vibrio cholerae ≥95% (estimated by SDS-PAGE)
  • 2mg
  • $ 357.00
  • Biosynth Carbosynth
  • Cholera toxin
  • 2 mg
  • $ 800.00
Total 47 raw suppliers
Chemical Property of CHOLERA TOXIN
Chemical Property:
  • PSA：0.00000 
  • LogP:0.00000 
  • Storage Temp.:0-6°C 
  • Solubility.:H2O: soluble10mg/mL 
Purity/Quality:

97% *data from raw suppliers

Cholera Toxin *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:T 
  • Statements: 24/25-52/53 
  • Safety Statements: 36/37-45-61 
MSDS Files:

Total 1 MSDS from other Authors

Useful:
  • General Description Cholera toxin (CT), also known as choleratoxin, choleragen, or choleragenoid, is a protein exotoxin produced by *Vibrio cholerae*. Its B subunit (CTB) binds specifically to ganglioside GM1 on host cell surfaces, facilitating the entry of the toxic A subunit, which induces severe diarrhea. The toxin's interaction with carbohydrate moieties, such as lactose in this study, enables its detection through fluorescence-based sensors like the tetraphenylethylene glycoconjugate (Lac-TPE), which exhibits enhanced fluorescence upon binding CTB due to aggregation-induced emission (AIE). This specificity underscores CT's role as a model for studying carbohydrate-protein interactions and its utility in diagnostic applications.
Refernces

Tetraphenylethylene-based glycoconjugate as a fluorescence "turn-on" sensor for cholera toxin

10.1002/asia.201100141

The study investigates the development of a fluorescence sensor for cholera toxin (CT) using tetraphenylethylene (TPE)-based glycoconjugates. The researchers synthesized TPE derivatives bearing lactosyl (Lac-TPE) and cellobiose (Cel-TPE) moieties through copper(I)-catalyzed "click reactions." Lac-TPE, due to its aggregation-induced emission (AIE) characteristics, exhibited a significant increase in fluorescence upon interaction with the cholera toxin B subunit (CTB), making it a potential sensor for CT detection. In contrast, Cel-TPE did not show any response to the toxin, highlighting the specificity of the interaction. The study demonstrates that the multivalent interactions between Lac-TPE and CTB enhance the binding affinity and specificity, leading to a "turn-on" fluorescence signal. This work provides a promising platform for detecting cholera toxin and investigating carbohydrate–protein interactions.

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